成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Xanthotoxin

8-Methoxypsoralen Struktur
298-81-7
CAS-Nr.
298-81-7
Bezeichnung:
Xanthotoxin
Englisch Name:
8-Methoxypsoralen
Synonyma:
XANTHOTOXIN;METHOXSALEN;Uvadex;Xanthoxin;AMMOIDIN;9-Methoxy-7H-furo[3,2-g]chromen-7-one;8-MOP;Oxsoralen;Methoxalen;Methoxsale
CBNumber:
CB6733540
Summenformel:
C12H8O4
Molgewicht:
216.19
MOL-Datei:
298-81-7.mol

Xanthotoxin Eigenschaften

Schmelzpunkt:
148-150 °C(lit.)
Siedepunkt:
276.6°C (rough estimate)
Dichte
1.1344 (rough estimate)
Brechungsindex
1.4270 (estimate)
storage temp. 
Sealed in dry,Room Temperature
L?slichkeit
H2O: slightly soluble
Aggregatzustand
Needle-Like Crystals or Powder
Farbe
white to yellow
Wasserl?slichkeit
PRACTICALLY INSOLUBLE
Merck 
14,5988
BRN 
196453
LogP
1.523 (est)
CAS Datenbank
298-81-7(CAS DataBase Reference)
IARC
1 (Vol. 24, Sup 7, 100A) 2012
NIST chemische Informationen
Methoxsalen(298-81-7)
EPA chemische Informationen
Methoxsalen (298-81-7)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn,T
R-S?tze: 22-43-46-45-34
S-S?tze: 36/37-53-45-36/37/39-26
RIDADR  3216
WGK Germany  3
RTECS-Nr. LV1400000
10
TSCA  Yes
HS Code  29322090
Giftige Stoffe Daten 298-81-7(Hazardous Substances Data)
Toxizit?t LD50 i.p. in rats: 470 ±30 mg/kg (Hakim)
Bildanzeige (GHS) GHS hazard pictogramsGHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H317 Kann allergische Hautreaktionen verursachen. Sensibilisierung der Haut Kategorie 1A Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H341 Kann vermutlich genetische Defekte verursachen. Keimzellmutagenit?t Kategorie 2 Warnung P201,P202, P281, P308+P313, P405,P501
H351 Kann vermutlich Krebs verursachen. Karzinogenit?t Kategorie 2 Warnung P201, P202, P281, P308+P313, P405,P501
Sicherheit
P202 Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P261 Einatmen von Staub vermeiden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P302+P352 BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.
P308+P313 BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.

Xanthotoxin Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R22:Gesundheitssch?dlich beim Verschlucken.
R43:Sensibilisierung durch Hautkontakt m?glich.
R46:Kann vererbbare Sch?den verursachen.
R45:Kann Krebs erzeugen.
R34:Verursacht Ver?tzungen.

S-S?tze Betriebsanweisung:

S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Beschreibung

8-Methoxypsoralen (8-MOP) and other psoralens are naturally found in plants, including common fruit and vegetable crops.

Chemische Eigenschaften

White to cream-colored, crystalline solid; odorless. Slightly soluble in alcohol; practically insoluble in water. Combustible.

Verwenden

8-Methoxypsoralen, is used in Photochemotherapy (methoxsalen with long wave ultraviolet radiation) is indicated for the repigmentation of idiopathic vitiligo. It is also used in Photopheresis (methoxsalen with long wave ultraviolet radiation of white blood cells) is indicated for use with the UVAR* System in the palliative treatment of the skin manifestations of cutaneous T-cell lymphoma.

Indications

Methoxsalen has effects similar to those of trioxsalen. Methoxsalen is superior to trioxsalen in producing erythema and tanning and is the drug used in PUVA therapy. Methoxsalen is also available as a 1% lotion.

Definition

ChEBI: A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.

Allgemeine Beschreibung

Odorless white to cream-colored crystalline solid. Bitter taste followed by tingling sensation.

Air & Water Reaktionen

Sensitive to light and air. Insoluble in water.

Reaktivit?t anzeigen

8-Methoxypsoralen is incompatible with strong oxidizing agents.

Brandgefahr

Flash point data for 8-Methoxypsoralen are not available; however, 8-Methoxypsoralen is probably combustible.

Kontakt-Allergie

This fur(an)ocoumarin is an phototoxic compound that causes phototoxic dermatitis. Many plants of the Apiaceae–Umbelliferae and most of the Rutaceae family contain 5-methoxypsoralen and 8-methoxypsoralen. Their spectra is in the UVA range (300–360 nm). It is used in combination with UVA to treat various skin disorders such as psoriasis.

Sicherheitsprofil

Confirmed carcinogen. Poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. A drug used to treat slun diseases.

Environmental Fate

The industrial use of 8-MOP results in its release into the environment through multiple pathways, and its existence as a natural substance in plants further expands exposure to the environment. Airborne 8-MOP will exist in the vapor and particulate phases, and will be degraded in air by reaction with photochemically produced hydroxyl radicals, with an estimated half-life of approximately 1.2 h, it may also be subject to direct photolysis by sunlight. Particulate 8-MOP will be removed from the atmosphere by wet or dry deposition. If released into the soil, it is expected to have high mobility and is not expected to volatilize. 8-MOP does not biodegrade. In aqueous environments, 8-MOP is not expected to hydrolyze, it will, however, adsorb to suspended solids and sediment. Due to 8-MOP’Ks resistance to degradation by many routes, it is expected to remain in the environment for a prolonged period, and as such will also be subject to long-range transport. 8-MOP has an estimated bioconcentration factor (BCF) of 9, meaning that bioconcentration and bioaccumulation are low in aquatic organisms.

l?uterung methode

Purify xanthotoxin by recrystallisation from *C6H6/pet ether (b 60-80o) to give silky needles, or from EtOH/Et2O to give rhombic prisms or from hot H2O to give needles. It is soluble in aqueous alkali due to ring opening of the cyclic lactone but recyclises upon acidification. It has UV max in EtOH at 219, 249 and 300nm (log  4.32, 4.35 and 4.06) and 1H NMR in CDCl3 with at 7.76 (d, 1H, J 10 Hz), 7.71 (d, 1H, J 2.5 Hz), 7.38 (s, 1H), 6.84 (d, 1H, J 2.5 Hz), 6.39 (d, 1H, J 10 Hz) and 4.28 (s, 3H)ppm. [Nore & Honkanen J Heterocycl Chem 17 985 1980.] It is a DNA intercalator, is used in the treatment of dermal diseases, and is a human carcinogen [Tessman et al. Biochemistry 24 1669 1985.] [Beilstein 19 I 711, 19/6 V 15.]

Xanthotoxin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Xanthotoxin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 438)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Weibang Biotechnology Co., Ltd
+8615531157085
abby@weibangbio.com China 8810 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578
sales@hbmojin.com China 12835 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177
peter@yan-xi.com China 5857 58
Hangzhou Hyper Chemicals Limited
+86-0086-57187702781 +8613675893055
info@hyper-chem.com China 295 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806
sales@capot.com China 29791 60
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29880 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083
scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897
sales@biopurify.com China 3772 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58

298-81-7(Xanthotoxin)Verwandte Suche:


  • 8-Methoxy-2',3',6,7-furocoumarin
  • 8-methoxy-2’,3’,6,7-furocoumarin
  • 8-Methoxy-4',5',6,7-furocoumarin
  • 8-Methoxy-4',5':6,7-furocoumarin
  • 8-methoxy-4’,5’,6,7-furocoumarin
  • 8-methoxy-4’,5’:6,7-furocoumarin
  • 8-Methoxy-6,7-furanocoumarin
  • 8-Methoxyfuranocoumarin
  • 8-mopcapsules
  • 8-MP
  • 9-methoxy-7h-furo(3,2-g)(1)benzopyran-7-one
  • 9-Methoxy-7H-furo(3,2-g)benzopyran-7-one
  • Proralone-mop
  • Psoralen-mop
  • psoralon-mop
  • Puvalen
  • Puvamet
  • Xanthotoxine
  • AKOS 214-64
  • 8-METHOXYPSORALEN
  • 8-METHOXYPSORALENE
  • 9-methoxypsoralen
  • 9-METHOXYFURO[3,2-G][1]BENZOPYRAN-7-ONE
  • 9-methoxyfuro[3,2-g]chromen-7-one
  • Xanthotoxin,Methoxsalen
  • anthotoxin
  • ZANTHOTOXIN
  • TIMTEC-BB SBB005950
  • 8-Methoxy
  • Methoxsalene
  • NSC 45923
  • Vitpso
  • Methoxsalen(8-Methoxypsoralen、Xanthotoxin)
  • Xanthotoxin 〔8-Methoxypsoralen〕
  • 5-Benzofuranacrylic acid, 6-hydroxy-7-methoxy-, delta-lactone
  • 5-Benzofuranacrylicacid,6-hydroxy-7-methoxy-,δ-lactone
  • 6-Hydroxy-7-methoxy-5-benzofuranacrylic acid gamma-lactone
  • 6-hydroxy-7-methoxy-5-benzofuranacrylicaciddelta-lactone
  • 6-hydroxy-7-methoxy-5-benzofuranacrylicacidelta-lactone
  • 7-Furocoumarin
  • 7H-Furo[3,2-g][1]benzopyran-7-one, 9-methoxy-
  • 7H-Furo[3,2-g][1]benzopyran-7-one,9-methoxy-
  • 8-methoxy-(furano-3’.2’:6.7-coumarin)
  • 8-Methoxy-[furano-3'.2':6.7-coumarin]
  • 8-methoxy[furano-3’,2’:6,7-coumarin]
  • Ammodin
  • geroxalen
  • Meladinin
  • Meladinine
  • Meladoxen
  • Meloxine
  • Methoxa-Dome
  • Methoxaten
  • methoxsalen[qr]
  • NCI-C55903
  • New-Meladinin
  • Oxoralen
  • oxoralen-ultra
Copyright 2019 ? ChemicalBook. All rights reserved