Bosutinib Impurity 2 (N-Desmethyl Bosutinib)
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- CAS-Nr.
- 380843-81-2
- Englisch Name:
- Bosutinib Impurity 2 (N-Desmethyl Bosutinib)
- Synonyma:
- Desmethyl Bosutinib;Bosutinib Impurity 2 (N-Desmethyl Bosutinib);3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-
- CBNumber:
- CB67247990
- Summenformel:
- C25H27Cl2N5O3
- Molgewicht:
- 516.42
- MOL-Datei:
- 380843-81-2.mol
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Bosutinib Impurity 2 (N-Desmethyl Bosutinib) Eigenschaften
- Schmelzpunkt:
- 123-125 °C
- Siedepunkt:
- 655.4±55.0 °C(Predicted)
- Dichte
- 1.38±0.1 g/cm3(Predicted)
- pka
- 9.19±0.10(Predicted)
Sicherheit
Bosutinib Impurity 2 (N-Desmethyl Bosutinib) Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Proteolysis Targeting Chimera (PROTAC) is a novel approach to modern drug development programs that utilizes small compounds to target proteins for ubiquitination and degradation by proteasome. 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-3-quinolinecarbonitrile is a PROTAC compound, which has the potential to target oncogenic BCR-ABL for degradation. 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-3-quinolinecarbonitrile has also been employed in ligand-based pharmacophore modelling to identify c-Src inhibitors.
Bosutinib Impurity 2 (N-Desmethyl Bosutinib) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Bosutinib Impurity 2 (N-Desmethyl Bosutinib) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 20)Lieferanten
- Bosutinib Impurity 2 (N-Desmethyl Bosutinib)
- Desmethyl Bosutinib
- 3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-
- 380843-81-2
