Methoxycarbonyl-L-tert-leucine
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- CAS-Nr.
- 162537-11-3
- Englisch Name:
- Methoxycarbonyl-L-tert-leucine
- Synonyma:
- (S)-2-acetamido-3,3-dimethylbutanoic acid;MOC-L-tert.Leucine;N-Methoxycarbonyl-tert-leucine;(S)-2-(MethoxycarbonylaMino)-3,3-diMethylbutanoic acid;Moc-L-tle;Moc-Tle-OH;MOC-L-Norleucine;Moc-L-tert-lecine;MOC-L-tert. Leucin;Atazanavir USP RC A
- CBNumber:
- CB6663762
- Summenformel:
- C8H15NO4
- Molgewicht:
- 189.21
- MOL-Datei:
- 162537-11-3.mol
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Methoxycarbonyl-L-tert-leucine Eigenschaften
- Schmelzpunkt:
- 1090C
- Siedepunkt:
- 320.9±25.0 °C(Predicted)
- Dichte
- 1.126±0.06 g/cm3(Predicted)
- Dampfdruck
- 0Pa at 25℃
- storage temp.
- 2-8°C
- L?slichkeit
- Soluble in ethyl acetate and methanol.
- pka
- 4.46±0.10(Predicted)
- Aggregatzustand
- powder
- Farbe
- White to off-white
- Wasserl?slichkeit
- 26.4g/L at 20℃
- InChI
- InChI=1S/C8H15NO4/c1-8(2,3)5(6(10)11)9-7(12)13-4/h5H,1-4H3,(H,9,12)(H,10,11)/t5-/m1/s1
- InChIKey
- NWPRXAIYBULIEI-RXMQYKEDSA-N
- SMILES
- C(O)(=O)[C@H](C(C)(C)C)NC(OC)=O
- LogP
- 0.832 at 21℃
Methoxycarbonyl-L-tert-leucine Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
White Solid
Verwenden
The coupling of the two key intermediates, N-(methoxycarbonyl)-l-tert-leucine acylated benzyl hydrazine and chloromethyl ketone, via an S N 2 reaction furnished the amino ketone in high yield under our optimized conditions in practical synthesis of the HIV Protease Inhibitor Atazanavir via a Highly diastereoselective Reduction Approach.
Methoxycarbonyl-L-tert-leucine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Methoxycarbonyl-L-tert-leucine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 454)Lieferanten
162537-11-3()Verwandte Suche:
- (S)-2-Methoxycarbonylamino-3,3-dimethylbutyric acid
- Methoxycarbonyl-L-tert-leucine
- N-(Methoxycarbonyl)-3-methyl-L-valine
- Atazanavir related coMpound A
- MOC-L-tert. Leucin
- L-Valine,N-(Methoxycarbonyl)-3-Methyl-
- Moc-L-tert-lecine
- (S)-2-(Methoxycarbonyl)-3,3-diMethylbutanoic acid
- Methyl Carbonyl L-tert Leucine
- (2S)-2-ACETAMIDO-3,3-DIMETHYLBUTANOIC ACID
- N-Moc-L-tert-Leucine
- (S)-N-(METHOXYCARBONYL)-TERT-LEUCINE
- Methylcarbonyl-L-t-Leucine
- Atazanavir USP Related Compound A
- Methoxycarbonyl-L-tert-leucinef
- Atazanavir side chain
- Atazanavir Impurity 15
- Atazanavir USP RC A
- N-Methoxycarbonyl-L-tert-leucine,98%
- Methoxycarbonyl-L-tert-leucine USP/EP/BP
- Moc-Tle-OH
- Atazanavir Related Compund A (Methoxycarbonyl-L-tert-leucine)
- Atazanavir Related Compound A ((S)-2-[(Methoxycarbonyl)amino]-3,3-dimethylbutanoic acid) (1044356)
- MOC-L-tert.Leucine
- N-Methoxycarbonyl-tert-leucine
- (S)-2-(MethoxycarbonylaMino)-3,3-diMethylbutanoic acid
- (S)-2-acetamido-3,3-dimethylbutanoic acid
- MOC-L-Norleucine
- Atazanavir Sulfate EP Impurity K
- Moc-L-tle
- N-(Methoxycarbonyl)-tert-L-leucine
- Azanavir EP Impurity K
- Atazanavir Sulfate Impurity K
- 162537-11-3
- C38H54N6O11S
- Amino Acid Derivatives
- Amino Acids 13C, 2H, 15N
- Amino Acids & Derivatives
- Chiral Reagents
