ANTI-HUMAN VIMENTIN Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Monoclonal Anti-Vimentin antibody has been used in western blotting and immunocytochemistry.
Allgemeine Beschreibung
Vimentin is encoded by a single-copy gene mapped to human chromosome 10p13. 53kDa vimentin protein belongs to type III intermediate filament (IF) family and is specifically expressed in normal mesenchymal cells. Vimentin protein with 466 amino acids is characterized with a highly conserved a-helical “rod” domain that is flanked by non-α-helical amino- terminal “head” and carboxy-terminal “tail” domain.
Biochem/physiol Actions
Vimentin is the major cytoskeletal component in immature glia. It is an intermediate filament protein and serves as a substrate for several caspases. The cleavage of this protein by caspase dismantles intermediate filaments and promotes apoptosis.
ANTI-HUMAN VIMENTIN Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
