PSI-7977-13C-d3 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

PSI-7977-¹³C-d₃ is intended for use as an internal standard for the quantification of PSI-7977 by GC- or LC-MS. PSI-7977 is a phosphoramidate prodrug of PSI-7851, a nucleoside analog that, when phosphorylated, inhibits the RNA-dependent RNA polymerase of hepatitis C virus (EC₅₀ = 92 nM). PSI-7977 is effective in vitro and in vivo.

Verwenden

PSI-7977-13CD3 is the isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

PSI-7977-13C-d3 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

PSI-7977-13C-d3 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
Shanghai Payne Pharmaceutical Technology Co.Ltd	021-58123769 18678586262	info@paynepharm.com	China	1354	58
Artis Biotech Co. Ltd.	0575-18780151478 18582380095	sales@artisbio.com	China	3044	58
Shanghai Payne Pharmaceutical Technology Co.Ltd	021-58123769 17721400256	info@paynepharm.com	China	1285	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11974	58
Nanjing Shizhou Biology Technology Co.,Ltd	17301488900	judy.xia@synzest.com	China	12582	58
Hubei Moco Chemical Co., Ltd.	18627753421 18627756402	3001009495@qq.com	China	19063	58
United States Biological	--	sales@advtechind.com	United States	6075	58

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• [13C,2H3]-Sofosbuvir
• isopropyl((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-(methyl-13C-d3)tetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
• Sofosbuvir 13CD3Q: What is Sofosbuvir 13CD3 Q: What is the CAS Number of Sofosbuvir 13CD3 Q: What is the storage condition of Sofosbuvir 13CD3 Q: What are the applications of Sofosbuvir 13CD3
• PSI-7977-13C-d3
• 2070009-25-3
• C2113CH26D3FN3O9P