2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE
|
|
- CAS-Nr.
- 182004-65-5
- Englisch Name:
- 2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE
- Synonyma:
- IN1281;KB-R7943;KB-R7943 MESYLATE;KB-R7943 - CAS 182004-65-5 - Calbiochem;-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE;2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE;S-[4-[(4-Nitrobenzyl)oxy]phenethyl]isothiourea Methanesulfonate;4-((4-Nitrobenzyl)oxy)phenethyl carbaMiMidothioate Methanesulfonate;S-[4-[(4-Nitrobenzyl)oxy]phenethyl]isothiourea Methanesulfonate >2-(2-(4-(4-NITROBENZYLOXY)PHENYL)ETHYL)ISOTHIOUREA, METHANE SULFONATE
- CBNumber:
- CB6422033
- Summenformel:
- C17H21N3O6S2
- Molgewicht:
- 427.49
- MOL-Datei:
- 182004-65-5.mol
|
2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE Eigenschaften
- Schmelzpunkt:
- >214°C (dec.)
- storage temp.
- Inert atmosphere,2-8°C
- L?slichkeit
- Soluble in DMSO (up to 50 mg/ml).
- Aggregatzustand
- White crystalline solid
- Farbe
- Tan
- Stabilit?t:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Bildanzeige (GHS) |
|
Alarmwort |
Warnung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H400 |
Sehr giftig für Wasserorganismen. |
Kurzfristig (akut) gew?ssergef?hrdend |
Kategorie 1 |
Warnung |
src="/GHS09.jpg" width="20" height="20" /> |
P273, P391, P501 |
|
Sicherheit |
P273 |
Freisetzung in die Umwelt vermeiden. |
P391 |
Verschüttete Mengen aufnehmen. |
P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
|
2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
KB-R7943 Mesylate is a selective inhibitor of the reverse mode of Na+/Ca2+ exchange in cells expressing NCX1.
Allgemeine Beschreibung
A cell-permeable inhibitor of the influx/reverse mode of the Na
+/Ca
2+ exchanger (NCX) (IC
50 = 4.3 μM for NCX1, 4.7 μM for NCX2, and 1.4 μM for NCX3). Directly modulates Na
+/Mg
2+ exchange in a Ca
2+-dependent manner. Reported ot offer neuronal and cardio-protection against ischemic injury. Also inhibits nicotinic acetylcholine receptors and NMDA receptor channels (IC
50<10 μM).
Biologische Aktivit?t
Potent, selective inhibitor of the reverse mode of the Na + /Ca 2+ exchanger (IC 50 = 0.7 mM). Does not affect Na + -dependent transport systems, Na + channels or ionotropic glutamate receptors.
2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 106)Lieferanten
182004-65-5()Verwandte Suche:
- Carbamimidothioic acid 2-[4-[(4-nitrophenyl)methoxy]phenyl]ethyl ester methanesulfonate
- Carbamimidothioic acid 2-[4-[(4-nitrophenyl)methoxy]phenyl]ethyl ester monomethanesulfonate
- KB-R7943
- KB-R7943 MESYLATE
- 2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE
- 2-(2-(4-(4-NITROBENZYLOXY)PHENYL)ETHYL)ISOTHIOUREA, METHANE SULFONATE
- S-[4-[(4-Nitrobenzyl)oxy]phenethyl]isothiourea Methanesulfonate
- 4-((4-Nitrobenzyl)oxy)phenethyl carbaMiMidothioate Methanesulfonate
- S-[4-[(4-Nitrobenzyl)oxy]phenethyl]isothiourea Methanesulfonate
- KB-R7943 - CAS 182004-65-5 - Calbiochem
- IN1281
- KB R7943; KB-R 7943; KBR7943; 182004-65-5; KB-R7943 MESYLATE; 2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE; IN1281; KB-R 7943
- S-[4-[(4-Nitrobenzyl)oxy]phenethyl]isothiourea Methanesulfonate >
- Carbamimidothioic Acid 4-[(4-Nitrobenzyl)oxy]phenethyl Ester Methanesulfonate
- -[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE
- 182004-65-5
- C16H17N3O3SCH3SO3H
- C17H21N3O6S2
- C16H17N3O3SCH4O3S
- CH4O3SC16H17N3O3S
- Signalling
- Ion transporter and other ion channel