trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Oxotremorine M is a non-selective muscarinic (M) acetylcholine receptor agonist that induces phosphoinositide hydrolysis in mouse ileum isolated from wild-type, M₂, M₃, and M₂/M₃ knockout mice (EC₅₀s = 0.36, 0.52, 1.62, and 1.48 μM, respectively). It also increases M₄-induced inhibition of calcium currents in NG108-15 mouse neuroblastoma X rat glioma hybrid cells (EC₅₀ = 0.14 μM). Oxotremorine M inhibits KCNQ2/3 potassium currents in Xenopus oocytes expressing M₁ receptors and KCNQ2/3 potassium channels (IC₅₀ = 1.1 μM). It also directly inhibits KCNQ2/3 potassium channels, decreasing KCNQ2/3 potassium currents in Xenopus oocytes lacking muscarinic receptors in a dose-dependent manner.

Verwenden

Oxotremorine M is a muscarinic receptor agonist.

trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38631	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52924	58
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185 18149758185	sales-cpd@caerulumpharma.com	China	3466	58
BOC Sciences	--	info@bocsci.com	USA	0	65
Shanghai hongqu biomedical technology co. LTD	88888888888	hongquchem@qq.com	China	5132	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8140	58
Zhengzhou Akem Chemical Co., Ltd	13303867194	3001317055@qq.com	China	9974	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840 15801484223;	psaitong@jm-bio.com	China	29774	58

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• trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide
• Oxotremorine M (iodide)
• CPD3509
• 3854-04-4