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Aurora Kinase Inhibitor II

Aurora Kinase Inhibitor II Struktur
331770-21-9
CAS-Nr.
331770-21-9
Englisch Name:
Aurora Kinase Inhibitor II
Synonyma:
IUN-70219;Aurora kinase inhibitor-2;N-(4-((6,7-Dimethoxyquinazolin-4-yl)amino)phenyl)benzamide;Benzamide, N-[4-[(6,7-dimethoxy-4-quinazolinyl)amino]phenyl]-;inhibit,Aurora-A,Aurora kinase inhibitor2,Aurora Kinase,ATP-competitive,Aurora kinase inhibitor 2,Aurora kinase inhibitor-2,Aurora-B,Inhibitor
CBNumber:
CB63136779
Summenformel:
C23H20N4O3
Molgewicht:
400.43
MOL-Datei:
331770-21-9.mol

Aurora Kinase Inhibitor II Eigenschaften

Siedepunkt:
518.6±50.0 °C(Predicted)
Dichte
1.321±0.06 g/cm3(Predicted)
storage temp. 
4°C, protect from light
L?slichkeit
DMF:0.25(Max Conc. mg/mL);0.62(Max Conc. mM)
DMF:PBS(pH7.2) (1:2):0.33(Max Conc. mg/mL);0.82(Max Conc. mM)
DMSO:2.5(Max Conc. mg/mL);6.2(Max Conc. mM)
Aggregatzustand
A crystalline solid
pka
13.01±0.70(Predicted)
Farbe
White to yellow

Sicherheit

Aurora Kinase Inhibitor II Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. Aurora kinase inhibitor II is a cell-permeable anilinoquinazoline that blocks the activity of Aurora A (IC50 = 0.39 μM). In MCF-7 cells, it blocks proliferation with an IC50 value of 1.25 μM.

Aurora Kinase Inhibitor II Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Aurora Kinase Inhibitor II Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 25)Lieferanten
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TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
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InvivoChem 		+1-708-310-1919 +1-13798911105
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TargetMol Chemicals Inc.
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Aladdin Scientific 		+1-+1(833)-552-7181
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Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266
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Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9806 58
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994
 2853530910@QQ.com China 8011 62
Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720
 lucy@atkchemical.com China 9952 58
MQ (shanghai) Pharmaceuticals Co., Ltd. 13761635123
 1014988033@qq.com China 5009 55
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6777 58
  • Aurora kinase inhibitor-2
  • IUN-70219
  • N-(4-((6,7-Dimethoxyquinazolin-4-yl)amino)phenyl)benzamide
  • inhibit,Aurora-A,Aurora kinase inhibitor2,Aurora Kinase,ATP-competitive,Aurora kinase inhibitor 2,Aurora kinase inhibitor-2,Aurora-B,Inhibitor
  • Benzamide, N-[4-[(6,7-dimethoxy-4-quinazolinyl)amino]phenyl]-
  • 331770-21-9
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