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VU0483605

VU0483605 Struktur
1623101-11-0
CAS-Nr.
1623101-11-0
Englisch Name:
VU0483605
Synonyma:
VU0483605;3-Chloro-N-(3-chloro-4-(4-chloro-1,3-dioxoisoindolin-2-yl)phenyl)picolinamide;3-chloro-N-[3-chloro-4-(4-chloro-1,3-dioxoisoindol-2-yl)phenyl]pyridine-2-carboxamide;2-Chloro-N-[3-chloro-4-(4-chloro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)phenyl]nicotinamide;3-Chloro-N-[3-chloro-4-(4-chloro-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenyl]-2-pyridinecarboxamide;3-chloro-N-[3-chloro-4-(4-chloro-1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)phenyl]pyridine-2-carboxamide;2-Pyridinecarboxamide, 3-chloro-N-[3-chloro-4-(4-chloro-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenyl]-;Inhibitor,inhibit,VU0483605,Metabotropic glutamate receptors,allosteric modulator,brain penetrant,metabotropic glutamate,VU 0483605,mGluR,VU-0483605
CBNumber:
CB63067594
Summenformel:
C20H10Cl3N3O3
Molgewicht:
446.67
MOL-Datei:
1623101-11-0.mol

VU0483605 Eigenschaften

Dichte
1.625±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
≤20mg/ml in DMSO;20mg/ml in dimethyl formamide
Aggregatzustand
crystalline solid
pka
9.39±0.70(Predicted)
Farbe
Light yellow to orange

Sicherheit

VU0483605 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

VU 0483605 is a positive allosteric modulator of metabotropic glutamate receptors (mGluRs) that preferentially binds mGlu1 over mGlu4 (1,2). VU 0483605 is a mGlu1 antagonist and has potential therapeutic properties for treating schizophrenia.

VU0483605 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

VU0483605 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 38)Lieferanten
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BOC Sciences 		+1-631-485-4226
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TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
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Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
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Amadis Chemical Company Limited 		571-89925085
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ELSA BIOTECHNOLOGY CO.,LTD. 15261860116
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Pharmacodia (Beijing) Co.,Ltd +86-400-851-9921
sales@pharmacodia.com China 2317 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
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Shanghai Yunpun industrial Co.,Ltd 21-61726900 15202122459
 sales@yunpun.com China 488 58
Lynnchem 86-(0)29-85992781 17792393971
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Nanjing KaiMubo Pharmaceutical Co., Ltd. 025-66162170
China 7181 55
  • VU0483605
  • 2-Chloro-N-[3-chloro-4-(4-chloro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)phenyl]nicotinamide
  • 3-Chloro-N-(3-chloro-4-(4-chloro-1,3-dioxoisoindolin-2-yl)phenyl)picolinamide
  • 3-Chloro-N-[3-chloro-4-(4-chloro-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenyl]-2-pyridinecarboxamide
  • 2-Pyridinecarboxamide, 3-chloro-N-[3-chloro-4-(4-chloro-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenyl]-
  • 3-chloro-N-[3-chloro-4-(4-chloro-1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)phenyl]pyridine-2-carboxamide
  • 3-chloro-N-[3-chloro-4-(4-chloro-1,3-dioxoisoindol-2-yl)phenyl]pyridine-2-carboxamide
  • Inhibitor,inhibit,VU0483605,Metabotropic glutamate receptors,allosteric modulator,brain penetrant,metabotropic glutamate,VU 0483605,mGluR,VU-0483605
  • 1623101-11-0
  • C20H10Cl3N3O3
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