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Verinurad

Verinurad Struktur
1352792-74-5
CAS-Nr.
1352792-74-5
Englisch Name:
Verinurad
Synonyma:
CS-2466;HY-16733;RDEA3170;Verinurad;Verinurad sodium;Verinurad (RDEA3170);Sialyllactose Impurity 3;2-((3-(4-cyanonaphthalen-1-yl)pyridin-4-yl)thio)-2-methylpropanoic acid;2-[[3-(4-Cyano-1-naphthalenyl)-4-pyridinyl]thio]-2-methylpropanoic acid;Propanoic acid, 2-[[3-(4-cyano-1-naphthalenyl)-4-pyridinyl]thio]-2-methyl-
CBNumber:
CB63041475
Summenformel:
C20H16N2O2S
Molgewicht:
348.42
MOL-Datei:
1352792-74-5.mol

Verinurad Eigenschaften

Schmelzpunkt:
204 - 207°C
Siedepunkt:
566.7±50.0 °C(Predicted)
Dichte
1.34±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
L?slichkeit
DMSO (Slightly), Methanol (Slightly)
pka
2.91±0.10(Predicted)
Aggregatzustand
Solid
Farbe
Off-White to Pale Brown

Sicherheit

Verinurad Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Verinurad is an inhibitor of urate anion transporter 1 (URAT1; IC50 = 0.025 μM for the human transporter). It is selective for human URAT1 over rat URAT1 (IC50 = 41 μM), as well as human organic anion transporter 1 (OAT1) and OAT4 (IC50s = 4.6 and 5.9 μM, respectively).

Verwenden

Verinurad is a second generation selective uric acid reabsorption inhibitor.

Verinurad Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Verinurad Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 74)Lieferanten
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  • Verinurad
  • 2-[[3-(4-Cyano-1-naphthalenyl)-4-pyridinyl]thio]-2-methylpropanoic acid
  • CS-2466
  • 2-((3-(4-cyanonaphthalen-1-yl)pyridin-4-yl)thio)-2-methylpropanoic acid
  • RDEA3170
  • HY-16733
  • Verinurad (RDEA3170)
  • Propanoic acid, 2-[[3-(4-cyano-1-naphthalenyl)-4-pyridinyl]thio]-2-methyl-
  • Verinurad sodium
  • Urate transporter 1,Verinurad,Inhibitor,SLC22A12,inhibit,RDEA 3170,URAT1,RDEA-3170
  • Sialyllactose Impurity 3
  • 1352792-74-5
  • api
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