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(R)-1-benzyl-5-methyl-1,4-diazepane

(R)-1-benzyl-5-methyl-1,4-diazepane Struktur
1620097-06-4
CAS-Nr.
1620097-06-4
Englisch Name:
(R)-1-benzyl-5-methyl-1,4-diazepane
Synonyma:
(R)-1-benzyl-5-methyl-1,4-diazepane;(5R)-1-benzyl-5-methyl-1,4-diazepane;Relebactam Impurity 4;Suvorexant Impurity 27;Suvorexant (MK-4305) intermediate;(R)-1-benzyl-5-methyl-1,4-diazepane(For export only);(5S)-Hexahydro-5-methyl-1-(phenylmethyl)-1H-1,4-diazepine;(5R)-Hexahydro-5-methyl-1-(phenylmethyl)-1H-1,4-diazepine;1H-1,4-Diazepine, hexahydro-5-methyl-1-(phenylmethyl)-, (5R)-;Suvorexant intermediate (5R)-Hexahydro-5-methyl-1-(phenylmethyl)-1H-1,4-diazepine
CBNumber:
CB63040519
Summenformel:
C13H20N2
Molgewicht:
204.31
MOL-Datei:
1620097-06-4.mol

(R)-1-benzyl-5-methyl-1,4-diazepane Eigenschaften

Siedepunkt:
296.1±28.0 °C(Predicted)
Dichte
0.974±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
10.65±0.40(Predicted)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
Sicherheit
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

(R)-1-benzyl-5-methyl-1,4-diazepane Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

(5R)-1-Benzyl-5-methyl-1,4-diazepane is a synthetic substance with inhibitory activity on calcium channels. It has been shown to be useful for the treatment of epilepsy and other neurological disorders in animal models. 

synthetische

(R)-4-benzyl-7-methyl-1,4-diazepan-2,5-dione(6 mmol)Was dissolved in 60 ml of dry THF, and 1.35 g of LiAlH4 (36 mmol) was added portionwise under ice-cooling, and stirred at 25℃ for 4 h.After cooling to -10 ℃, 1.5 ml of H20 was added and 1.5 ml of 15% NaOH, 4.5 ml of H20 and a portion of MgS04 were added, stirred for 1 h, suction filtered and dried to afford 1.2 g of an oil yield 97.56%。    Synthesis of (R)-1-benzyl-5-methyl-1,4-diazepane

(R)-1-benzyl-5-methyl-1,4-diazepane Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


(R)-1-benzyl-5-methyl-1,4-diazepane Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 60)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
PharmOrgSyn Laboratories Co., Ltd.
+86-021-38228826 +86-13916602830
sales@pharmorgsyn.cn China 140 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32951 60
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29885 58
Zhejiang ZETian Fine Chemicals Co. LTD
+8618957127338
stella@zetchem.com China 2136 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873
sales@chemdad.com China 39894 58
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63687 58
Coresyn Pharmatech Co., Ltd.
+86-571-86626709 +86-18157142896
cbc@coresyn.com China 9984 58
Jiangsu Guotai Guomian Trading Co. Ltd.
+86-512-58916079 +86-13601562190
pharmachem@gtgmt.com China 148 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8617865335152
Mandy@hangyubiotech.com China 10986 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652
info@fdachem.com China 20288 58

  • (5R)-Hexahydro-5-methyl-1-(phenylmethyl)-1H-1,4-diazepine
  • Suvorexant intermediate (5R)-Hexahydro-5-methyl-1-(phenylmethyl)-1H-1,4-diazepine
  • Suvorexant (MK-4305) intermediate
  • 1H-1,4-Diazepine, hexahydro-5-methyl-1-(phenylmethyl)-, (5R)-
  • (R)-1-benzyl-5-methyl-1,4-diazepane(For export only)
  • (R)-1-benzyl-5-methyl-1,4-diazepane
  • (5R)-1-benzyl-5-methyl-1,4-diazepane
  • Suvorexant Impurity 27
  • (5S)-Hexahydro-5-methyl-1-(phenylmethyl)-1H-1,4-diazepine
  • Relebactam Impurity 4
  • 1620097-06-4
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