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Carboxyatractyloside

Carboxyatractyloside Struktur
77228-71-8
CAS-Nr.
77228-71-8
Englisch Name:
Carboxyatractyloside
Synonyma:
Carboxyatractylosidetripotassiumsal;Carboxyatractyloside tripotassium salt;Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-;Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-;(2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioic acid
CBNumber:
CB62677293
Summenformel:
C31H46O18S2
Molgewicht:
770.81
MOL-Datei:
77228-71-8.mol

Carboxyatractyloside Eigenschaften

Dichte
1.58±0.1 g/cm3(Predicted)
storage temp. 
-20°C
L?slichkeit
H2O: ≥10mg/mL
pka
-3?+-.0.18(Predicted)
Aggregatzustand
solid
Farbe
white

Sicherheit

Kennzeichnung gef?hrlicher T
R-S?tze: 23/24/25
S-S?tze: 36/37-45
RIDADR  UN 2811 6.1 / PGI
WGK Germany  3

Carboxyatractyloside Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Carboxyatractyloside potassium salt has been used as an activator of Ca2+-induced mPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) opening. It has also been used as a adenine nucleotide translocator (ANT) inhibitor to study the inhibition of oxidative phosphorylation in intact T98G glioma cells.

Biochem/physiol Actions

Carboxyatractyloside is a highly selective inhibitor of cytosolic side-specific mitochondrial ADP/ATP carrier; i.e. adenine nucleotide translocase (ANT); causes stabilization of the c conformation of ANT leading to permeability transition pore (PTP) opening, loss of mitochondrial membrane potential, and apoptosis.

Carboxyatractyloside Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Carboxyatractyloside Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 125)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shanghai Zheyan Biotech Co., Ltd. 		18017610038
zheyansh@163.com CHINA 3619 58
Chengdu Greenpure Biopharma CO.,Ltd 		18283602253; +8618283602253
 jancyzheng@gcgreenpure.com China 953 58
Chengdu GLP biotechnology Co Ltd 		028-87075086 13350802083
 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd. 		+8618080483897
 sales@biopurify.com China 3772 58
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Shanghai Standard Technology Co., Ltd. 		18502101150
ft-sales@nature-standard.com CHINA 1923 58
career henan chemical co 		+86-0371-86658258 +8613203830695
 factory@coreychem.com China 29810 58
Wuhan ChemNorm Biotech Co.,Ltd. 		+86-27-8439 4403 18971486879
 sales@chemnorm.com CHINA 2935 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Hubei Ipure Biology Co., Ltd 		+8613367258412
 ada@ipurechemical.com China 10319 58

77228-71-8()Verwandte Suche:

  • (2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioic acid
  • Carboxyatractyloside tripotassium salt
  • Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-
  • Carboxyatractylosidetripotassiumsal
  • Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-
  • 77228-71-8
  • C31H46O18S2
  • reagent
  • standard substance
  • chemical reagent
  • herbal extract
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
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