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5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate

5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate Struktur
52248-03-0
CAS-Nr.
52248-03-0
Englisch Name:
5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate
Synonyma:
VHPOFDUCFKOUHV-XKGORWRGSA-O;S-(5'-Adenosyl)-L-methionine tosylate;P-toluenesulfonic acid adenosylmethionine;P-toluenesulfonic acid adenosylmethionine (SAMe);S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt;5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate;5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate;S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt >=80% (HPLC), >=80% (spectrophotometric assay);((S)-3-Amino-3-carboxypropyl)(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonium 4-methylbenzenesulfonate
CBNumber:
CB62616975
Summenformel:
C22H30N6O8S2
Molgewicht:
570.64
MOL-Datei:
52248-03-0.mol

5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate Eigenschaften

Schmelzpunkt:
78℃
storage temp. 
-20°C
L?slichkeit
DMF: 5 mg/ml; DMSO: 10 mg/ml; PBS (pH 7.2): 10 mg/ml
Aggregatzustand
A crystalline solid
Farbe
White to yellow
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
WGK Germany  3
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt has been used for cell proliferation assay. It has also been used for methylation assay.

Allgemeine Beschreibung

S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt is used for the treatment of depression, liver cirrhosis, cholestasis and degenerative joint disease.

Biochem/physiol Actions

Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury.

5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 39)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Alchem Pharmtech,Inc. 		8485655694
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SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289
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BOC Sciences 		16314854226; +16314854226
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Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
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TargetMol Chemicals Inc.
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Aladdin Scientific 		+1-+1(833)-552-7181
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Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
Syncozymes (Shanghai) Co.,Ltd. 021-68187180-819 13681683526
 lchen@syncozymes.com China 227 55
Beijing Qinling Mountains Pharmaceutical Co., Ltd. 010-61241352 18901327973
 834537306@qq.com China 530 58
  • 5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate
  • ((S)-3-Amino-3-carboxypropyl)(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonium 4-methylbenzenesulfonate
  • VHPOFDUCFKOUHV-XKGORWRGSA-O
  • S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt >=80% (HPLC), >=80% (spectrophotometric assay)
  • P-toluenesulfonic acid adenosylmethionine
  • P-toluenesulfonic acid adenosylmethionine (SAMe)
  • 5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate
  • S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt
  • S-(5'-Adenosyl)-L-methionine tosylate
  • 52248-03-0
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