2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one
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- CAS-Nr.
- 1013916-37-4
- Englisch Name:
- 2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one
- Synonyma:
- Palbociclib intermediates;-5-methyL;oro-8-cycL;3-d]pyriMidin-7(8H)-one;Palbociclib Impurity 105;Palbociclib Intermediate2;2-chloro-8-cyclopentyl-5-Me;Palbociclib impurity 703-201;pyrido[2,3-d]pyrimidin-7(8H)-one;2-chloro-8-cyclopentyl-5-Methylpyrido[2
- CBNumber:
- CB62554161
- Summenformel:
- C13H14ClN3O
- Molgewicht:
- 263.72
- MOL-Datei:
- 1013916-37-4.mol
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2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Eigenschaften
- Schmelzpunkt:
- 176 - 178°C
- Siedepunkt:
- 428.0±34.0 °C(Predicted)
- Dichte
- 1.346±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- L?slichkeit
- Chloroform (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 0.82±0.20(Predicted)
- Farbe
- Yellow to Dark Yellow
- Wasserl?slichkeit
- Slightly soluble in water.
- InChI
- InChI=1S/C13H14ClN3O/c1-8-6-11(18)17(9-4-2-3-5-9)12-10(8)7-15-13(14)16-12/h6-7,9H,2-5H2,1H3
- InChIKey
- BSKNQSYIDZUXQT-UHFFFAOYSA-N
- SMILES
- C1(Cl)=NC=C2C(C)=CC(=O)N(C3CCCC3)C2=N1
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one is used as an intermediate for Palbociclib, a CDK 4/6 inhibitor used to treat patients with hormone receptor (HR)-positive, HER-2-negative advanced or metastatic (cancer that has spread) breast cancer.
Verwenden
2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one is used as pharmaceutical intermediate.
2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 282)Lieferanten
1013916-37-4()Verwandte Suche:
- 2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one
- Pyrido[2,3-d]pyriMidin-7(8H)-one, 2-chloro-8-cyclopentyl-5-Methyl-
- 2-chloro-8-cyclopentyl-5-Me
- Palbociclib Intermediate2
- 2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (For Palbociclib)
- 2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7-one
- 2-chloro-8-cyclopentyl-5-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one
- 2-chloro-8-cyclopentyl-5-Methylpyrido[2
- 3-d]pyriMidin-7(8H)-one
- 2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one
- oro-8-cycL
- pyrido[2,3-d]pyrimidin-7(8H)-one
- 2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one,97%
- -5-methyL
- 2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one 2-
- 2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-...
- Palbociclib Impurity 105
- Palbociclib intermediates
- 2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]
- 2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMi
- 2-chloro-8-cyclopentyl-5-methoyrido-8H-pyrido[ 2,3-D]pyrimidin- 7 - one
- 2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-
- 2-chloro-8-cyclopentyl-5-methyl-8H-pyrido [2,3-D] pyridine
- Palbociclib impurity 703-201
- 1013916-37-4
- Anticancer
- 1013916-37-4
