FH 535
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- CAS-Nr.
- 108409-83-2
- Englisch Name:
- FH 535
- Synonyma:
- FH 535;CS-1433;FH 535(FH-535);FH 535 USP/EP/BP;FH535;FH 535;FH-535;β-Catenin/Tcf Inhibitor, FH535;β-Catenin/Tcf Inhibitor, FH535;FH-535, Wnt/beta-cantenin inhibitor;2,5-Dichloro-N-(2-Methyl-4-nitrophenyl)benzenesulfonaMide;N-(2-Methyl-4-nitrophenyl)-2,5-dichlorobenzenesulfonaMide
- CBNumber:
- CB62552602
- Summenformel:
- C13H10Cl2N2O4S
- Molgewicht:
- 361.2
- MOL-Datei:
- 108409-83-2.mol
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FH 535 Eigenschaften
- Schmelzpunkt:
- 141-142℃
- Siedepunkt:
- 526.3±60.0 °C(Predicted)
- Dichte
- 1.566±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO: soluble20mg/mL
- Aggregatzustand
- Yellow solid
- pka
- 5.83±0.10(Predicted)
- Farbe
- Tan
- Stabilit?t:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
- InChIKey
- AXNUEXXEQGQWPA-UHFFFAOYSA-N
FH 535 Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Dark Yellow Solid
Verwenden
Antagonizes Wnt/β-catenin/Tcf-mediated transcription as well as PPARγ and δ activity. Able to inhibit the recruitment of the co-activators β-catenin and GRIP1, both of which are activators for both pathways.
Biochem/physiol Actions
FH535 has the ability to block the development of colon cancer cells. It can change several cancer-associated biological processes. FH535 can also prevent PARylation of Axin2 in osteosarcoma cells.
FH 535 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
FH 535 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 120)Lieferanten
108409-83-2()Verwandte Suche:
- β-Catenin/Tcf Inhibitor, FH535
- FH 535(FH-535)
- FH535;FH 535;FH-535
- FH 535
- N-(2-Methyl-4-nitrophenyl)-2,5-dichlorobenzenesulfonaMide
- 2,5-Dichloro-N-(2-Methyl-4-nitrophenyl)benzenesulfonaMide
- 2,5-Dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide FH535
- β-Catenin/Tcf Inhibitor, FH535 - CAS 108409-83-2 - Calbiochem
- FH535, 98%, a cell-permeable compound that inhibits Wnt/β-catenin and PPAR
- Benzenesulfonamide, 2,5-dichloro-N-(2-methyl-4-nitrophenyl)-
- FH 535 USP/EP/BP
- CS-1433
- FH 535,Beta catenin,β-catenin,FH535,inhibit,FH-535,PPAR,Wnt,Inhibitor,Peroxisome proliferator-activated receptors
- β-Catenin/Tcf Inhibitor, FH535
- FH-535, Wnt/beta-cantenin inhibitor
- 108409-83-2
- API
- Aromatics
- Inhibitors
- Intermediates & Fine Chemicals
- Pharmaceuticals
