1-[(2-Phenylethyl)amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione
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- CAS-Nr.
- 376382-11-5
- Englisch Name:
- 1-[(2-Phenylethyl)amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione
- Synonyma:
- BRD 7389;BRD 7389
(BRD7389);BRD7389 >=98% (HPLC);Insulin Expression Inducer, BRD7389;BRD-7389, p90 ribosomal S6 kinase RSK inhibitor;1-Phenethylamino-3H-naphtho[1,2,3-de]quinoline-2,7-dione;1-(Phenethylamino)-2H-naphtho[1,2,3-de]quinoline-2,7(3H)-dione;1-[(2-Phenylethyl)amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione;1-[(2-Phenylethyl)amino]-naphtho-3H-[1,2,3-de]quinoline-2,7-dione;3H-Naphtho[1,2,3-de]quinoline-2,7-dione, 1-[(2-phenylethyl)aMino]-
- CBNumber:
- CB62518899
- Summenformel:
- C24H18N2O2
- Molgewicht:
- 366.41
- MOL-Datei:
- 376382-11-5.mol
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1-[(2-Phenylethyl)amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione Eigenschaften
- Siedepunkt:
- 655.0±55.0 °C(Predicted)
- Dichte
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- Store at +4°C
- L?slichkeit
- DMSO: >20mg/mL
- Aggregatzustand
- powder
- pka
- 11.31±0.40(Predicted)
- Farbe
- orange
- Stabilit?t:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Bildanzeige (GHS) |
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Alarmwort |
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Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H413 |
Kann für Wasserorganismen sch?dlich sein, mit langfristiger Wirkung. |
Langfristig (chronisch) gew?ssergef?hrdend |
Kategorie 4 |
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Sicherheit |
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1-[(2-Phenylethyl)amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
BRD7389 is an inhibitor of ribosomal S6 kinases (RSKs; IC
50s = 1.5, 2.4, and 1.2 μM for RSK1, RSK2, and RSK3, respectively). Through this action, BRD7389 causes mouse αTC1 pancreatic α cells to adopt several morphological and gene expression features of β cells, including increased insulin expression. BRD7389 also enhances glucose-stimulated insulin and glucagon secretion by pancreatic islet cells isolated from human donors with a low body mass index.
1-[(2-Phenylethyl)amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
1-[(2-Phenylethyl)amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 50)Lieferanten
376382-11-5()Verwandte Suche:
- BRD 7389
- 3H-Naphtho[1,2,3-de]quinoline-2,7-dione, 1-[(2-phenylethyl)aMino]-
- 1-[(2-Phenylethyl)amino]-naphtho-3H-[1,2,3-de]quinoline-2,7-dione
- 1-Phenethylamino-3H-naphtho[1,2,3-de]quinoline-2,7-dione
- 1-[(2-Phenylethyl)amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione
- Insulin Expression Inducer, BRD7389
- BRD 7389
(BRD7389)
- Insulin Expression Inducer, BRD7389 - CAS 376382-11-5 - Calbiochem
- BRD7389 >=98% (HPLC)
- BRD7389,cancer,S6K,Inhibitor,BRD 7389,colon,inhibit,RSK,islets,diabetes,BRD-7389,pancreatic,SNU-407,Ribosomal S6 Kinase (RSK)
- 1-(Phenethylamino)-2H-naphtho[1,2,3-de]quinoline-2,7(3H)-dione
- BRD-7389, p90 ribosomal S6 kinase RSK inhibitor
- 376382-11-5