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1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE

1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE Struktur
104113-71-5
CAS-Nr.
104113-71-5
Englisch Name:
1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE
Synonyma:
NPPI;TIMTEC-BB SBB003161;1-(1-NAPHTHYL)PIPERAZINE;1-(1-NAPHTHYL)PIPERAZINE HCL;1-(1-Naphthalenyl)piperazine;1-(Piperazin-1-yl)naphthalene;1-(1-Naphthyl)piperazine*2HCl;1-(Naphth-1-yl)piperazine diHCl;1-(Naphthalen-1-yl)piperazineHCl;1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE
CBNumber:
CB6244792
Summenformel:
C14H17ClN2
Molgewicht:
248.75
MOL-Datei:
104113-71-5.mol

1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE Eigenschaften

Schmelzpunkt:
235-237 °C
storage temp. 
Store at -20°C
L?slichkeit
H2O: soluble
Aggregatzustand
needles
Farbe
white
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
WGK Germany  3
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P304+P340 BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.
P405 Unter Verschluss aufbewahren.

1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

1-(1-Naphthyl)piperazine (1-NP) is a ligand for serotonin (5-hydroxytryptamine, 5-HT) receptors. It acts as an antagonist for 5-HT at 5-HT1 and 5-HT2 in rat cortical membranes with IC50 values of 6 and 1 nM, respectively. 1-NP also blocks contraction in the rat fundus induced by either 5-HT or tryptamine (IC50 = 1 nM for both agonists). 1-NP mimics the 5-HT1 agonist 1-(m-trifluoromethylphenyl)piperazine (TFMPP, ) in decreasing 5-HT receptor turnover and increasing serum corticosterone, suggesting that, in the absence of 5-HT, 1-NP may act as an agonist of the 5-HT1 receptor. However, in squirrel monkeys, 1-NP acts as a non-selective 5-HT receptor antagonist in altering operant behavior. 1-NP also binds to the human 5-HT6 receptor with an affinity comparable to that of 5-HT (Kis = 120 and 100 nM, respectively).

Verwenden

1-(1-Naphthyl)piperazinemiddotHCl is a mixed agonist/antagonist of the serotonin receptors.

1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • 1-(1-NAPHTHYL)PIPERAZINE
  • 1-(1-NAPHTHYL)PIPERAZINE HCL
  • 1-(1-NAPHTHYL)PIPERAZINE HYDROCHLORIDE
  • 1-(1-Naphthalenyl)piperazine
  • 1-(Piperazin-1-yl)naphthalene
  • 1-(Naphthalen-1-yl)piperazineHCl
  • 1-(1-Naphthyl)piperazine*2HCl
  • Piperazine, 1-(1-naphthalenyl)-, hydrochloride (1:1)
  • TIMTEC-BB SBB003161
  • NPPI
  • 1-NAPHTHALEN-1-YL-PIPERAZINE HYDROCHLORIDE
  • 1-(Naphth-1-yl)piperazine diHCl
  • Piperazine, 1-(1-naphthalenyl)-, monohydrochloride
  • 1 (1 Naphthyl) piperazine hydrochloride,1(1Naphthyl) piperazine hydrochloride
  • 104113-71-5
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