N-(9-Acetyl-6,9-dihydro-6-oxo-1H-purin-2-yl)acetamid
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- CAS-Nr.
- 3056-33-5
- Bezeichnung:
- N-(9-Acetyl-6,9-dihydro-6-oxo-1H-purin-2-yl)acetamid
- Englisch Name:
- N2,9-Diacetylguanine
- Synonyma:
- DIACETYL GUANINE;2,9-DIACETYLGUANINE;N2,9-DIACETYLGUANINE;2,9-DAG;9-diacetylguanine;N,9-DIACETYLGUANINE;2,9-DIACETATEGUANINE;2,9-Guanine Diacetate;N2,N9-Diacetylguanine;Acyclovir EP Impurity L
- CBNumber:
- CB6183086
- Summenformel:
- C9H9N5O3
- Molgewicht:
- 235.2
- MOL-Datei:
- 3056-33-5.mol
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N-(9-Acetyl-6,9-dihydro-6-oxo-1H-purin-2-yl)acetamid Eigenschaften
- Schmelzpunkt:
- 285 °C(lit.)
- Dichte
- 1.67±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- Aqueous Base (Slightly, Heated), DMSO (Slightly, Heated)
- Aggregatzustand
- Solid
- pka
- 8.37±0.20(Predicted)
- Farbe
- White to Light Beige
- InChI
- InChI=1S/C9H9N5O3/c1-4(15)11-9-12-7-6(8(17)13-9)10-3-14(7)5(2)16/h3H,1-2H3,(H2,11,12,13,15,17)
- InChIKey
- GILZZWCROUGLIS-UHFFFAOYSA-N
- SMILES
- C(NC1NC(=O)C2=C(N=1)N(C(C)=O)C=N2)(=O)C
- CAS Datenbank
- 3056-33-5(CAS DataBase Reference)
N-(9-Acetyl-6,9-dihydro-6-oxo-1H-purin-2-yl)acetamid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Beschreibung
N2,9-Diacetylguanine is a purine compound that can be prepared by acetylation of guanine with acetic anhydride. It can be used in many fields such as organic synthesis, biological research and pharmaceutical manufacturing. N2,9-Diacetylguanine can be prepared into 2-amino-6-halogenated purine under the action of two-step PEG-2000 phase transfer catalyst and TPPB phase transfer catalyst, and further through the corresponding CuX-catalyzed diazotization reaction, new 2-halogenated purine compounds can be efficiently synthesized
[2]. In addition, it can also be used as an intermediate for the antiviral drugs Ganciclovir and Aciclovir.
Chemische Eigenschaften
white or brownish crystalline powder
Verwenden
N2,9-Diacetylguanine (Acicclovir EP Impurity L) is used to synthesize acyclic analogues of deoxyguanosine.
Application
The alkylation of N2,N9- diacetylguanine (DAG) with 2-oxa-1, 4-butane-dioldiacetate to give N2-acetyl-9-{2-acetoxyethoxymethyl}- guanine (N9 isomer) and/or N2-acetyl-7-{2-acetoxyethoxymethyl}- guanine (N7 isomer) in exceptionally high regioselectivity[1].
N-(9-Acetyl-6,9-dihydro-6-oxo-1H-purin-2-yl)acetamid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
N-(9-Acetyl-6,9-dihydro-6-oxo-1H-purin-2-yl)acetamid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 416)Lieferanten
3056-33-5(N-(9-Acetyl-6,9-dihydro-6-oxo-1H-purin-2-yl)acetamid)Verwandte Suche:
- 2-ACETYLAMINO-6-OXO-9-ACETYLPURINE
- 2,9-DAG
- 2,9-DIACETATEGUANINE
- 9-diacetylguanine
- (9-acetyl-6,9-dihydro-6-oxo-1h-purin-2-yl)acetamide
- 2,9-Guanine Diacetate
- N-(9-acetyl-6,9-dihydro-6-oxo-1H-purin-2-yl)acetamide
- N,9-DIACETYLGUANINE
- 2,9-DIACETYLGUANINE(DIACETYLGUANINE)
- N2,9-DIACETYLGUANINE (DIACETYL GUANINE)
- N2,9-DIACETYLGUANINE [DIACETYL GUANINE]ACYCLOVIR
- 2-Acetamido-9-acetyl-6-oxopurine
- N(sup 2),9-diacetylguanine
- 2-(Acetylamino)-9-acetyl-1,9-dihydro-6H-purine-6-one
- 2-(Acetylamino)-9-acetyl-9H-purine-6(1H)-one
- N-(9-Acetyl-6-oxo-6,9-dihydro-1H-purin-2-yl)acetaMide
- N2,9-Diacetylguanine
- Acyclovir impurity 9/Acyclovir EP Impurity L/N-(9-acetyl-6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide
- Acyclovir (Aciclovir) EP Impurity L
- N-(1-acetyl-4-oxo-5H-imidazo[4,5-c]pyridin-6-yl)acetamide
- Acyclovir Impurity 4（Acyclovir EP Impurity L）
- N-(9-acetyl-6-oxo-3H-purin-2-yl)acetamide
- Acyclovir EP Impurity L
- N2,N9-Diacetylguanine
- Aciclovir EP Impurity L
- N2,9-Diacetylguanine>
- Acetamide, N-(9-acetyl-6,9-dihydro-6-oxo-1H-purin-2-yl)-
- N,9-Diacetylguanine USP/EP/BP
- Acicclovir EP Impurity L
- N(2),9-Diacetylguanine, 99%,
- 2,9-DIACETYLGUANINE
- DIACETYL GUANINE
- N2,9-DIACETYLGUANINE
- L.?N-(9-acetyl-6-oxo-6,9-dihydro-1h-purin-2-yl)acetamide(N2,9-diacetylguanine),
- Aciclovir (Acyclovir) EP Impurity L
- 3056-33-5
- 3056-33-6
- C9H9N5O3
- C9H9O3N5
- Purines
- Heterocyclic Building Blocks
- Building Blocks
- Building Blocks
- Heterocyclic Building Blocks
- Purines
- Biochemistry
- Nucleobases and their analogs
- Nucleosides, Nucleotides & Related Reagents
- Bases & Related Reagents
- Nucleotides
- Nucleotides and Nucleosides
- Purine
- Pyridines, Pyrimidines, Purines and Pteredines
