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4-Chlorbenzhydrylalkohol

4-Chlorobenzhydrol Struktur
119-56-2
CAS-Nr.
119-56-2
Bezeichnung:
4-Chlorbenzhydrylalkohol
Englisch Name:
4-Chlorobenzhydrol
Synonyma:
Chlorobenzhydrol;Cetirizine 4-Chlorobenzhydrol Impurity;AURORA KA-7061;4-CHLOROBENZHYDROL;Meclizine USP RC A;P-CHLORO BENZHYDROL;4-Chlorobenzohydrol;p-Chlorobenzohydrol;Benzhydrol, p-chloro-;Benzhydrol, 4-chloro-
CBNumber:
CB6151432
Summenformel:
C13H11ClO
Molgewicht:
218.68
MOL-Datei:
119-56-2.mol

4-Chlorbenzhydrylalkohol Eigenschaften

Schmelzpunkt:
58-60 °C (lit.)
Siedepunkt:
150-151°C 2,6mm
Dichte
1.1178 (rough estimate)
Brechungsindex
1.5260 (estimate)
Flammpunkt:
150-151°C/2.6mm
storage temp. 
2-8°C
L?slichkeit
insoluble
pka
13.34±0.20(Predicted)
Farbe
White to Off-White
Wasserl?slichkeit
insoluble
BRN 
2050235
CAS Datenbank
119-56-2(CAS DataBase Reference)
NIST chemische Informationen
Benzenemethanol, 4-chloro-«alpha»-phenyl-(119-56-2)
EPA chemische Informationen
Benzenemethanol, 4-chloro-.alpha.-phenyl- (119-56-2)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn
R-S?tze: 20/21/22-36/37/38
S-S?tze: 24/25-36-26
WGK Germany  3
TSCA  Yes
HS Code  29062990
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H412 Sch?dlich für Wasserorganismen, mit langfristiger Wirkung. Langfristig (chronisch) gew?ssergef?hrdend Kategorie 3 P273, P501
Sicherheit
P273 Freisetzung in die Umwelt vermeiden.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

4-Chlorbenzhydrylalkohol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Chemische Eigenschaften

white crystalline powder

Verwenden

4-Chlorobenzhydrol was used as internal standard to measure the N-demethyl antipyrine metabolite in urine by gas chromatography-mass spectrometry. It was also used in the identification of the antihistamine cetirizine as a relevant cross-reactant for the carbamazepine-specific enzyme-linked immunosorbent assay .

synthetische

Preparation of 4-Chlorobenzhydrol(4-CB):
about 5.0g(0.023 mol) of 4-chloro benzophenone was dissolved in 15 mL of isopropyl alcohol (IPA) and heated to 50°C followed by the addition of 0.265g(0.007 mol) of sodium borohydride as a lot with the temperature maintained at 65°C for 2 h. The reaction mixture was distilled to expel isopropyl alcohol up to 90 %. The resulting solution was cooled and treated with dil HCl (5 mL of conc. HCl in 20 mL of water). Finally the reaction mass was extracted with 15 mL of toluene. The toluene extract was washed withwater to pH-7. The compound obtained in this step was taken to next step without isolation but aliquot sample was concentrated, isolated and checked for melting point (m.p. = 58-60°C).

4-Chlorbenzhydrylalkohol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


4-Chlorbenzhydrylalkohol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 310)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Yanxi Chemical Co., Ltd.
+8617531190177
peter@yan-xi.com China 5858 58
Hebei Weibang Biotechnology Co., Ltd
+8617732866630
bess@weibangbio.com China 18155 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806
sales@capot.com China 29791 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21638 55
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29885 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
sales@sdzschem.com China 2930 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58
Hubei xin bonus chemical co. LTD
86-13657291602
linda@hubeijusheng.com CHINA 22963 58
Standardpharm Co. Ltd.
86-714-3992388
overseasales1@yongstandards.com United States 14332 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873
sales@chemdad.com China 39894 58

119-56-2(4-Chlorbenzhydrylalkohol)Verwandte Suche:


  • (4-Chlorophenyl)phenylmethanol
  • 4-chloro-alpha-phenyl-benzenemethano
  • 4-Chlorobenzohydrol
  • Benzhydrol, 4-chloro-
  • Benzhydrol, p-chloro-
  • AURORA KA-7061
  • P-CHLORO BENZHYDROL
  • 4-CHLOROPHENYL PHENYL CARBINOL
  • 4-CHLORO-ALPHA-PHENYL-BENZENEMETHANOL
  • 4-CHLORO-(ALPHA-PHENYL) BENZYL ALCOHOL
  • 4-CHLOROBENZHYDROL
  • 4-Chlorobenzhydryl alcohol
  • 4-CHLORO-O-PHENYLBENZYL ALCOHOL
  • 4-CHLORODIPHENYLCARBINOL
  • 4-CHLORODIPHENYLMETHANOL
  • Benzenemethanol, 4-chloro-.alpha.-phenyl-
  • 4-Chlorodiphenylmethanol~4-Chlororphenyl phenyl carbinol
  • 4-CHLOROBENZHYDROL 98+%
  • 4-Chloro-a-phenyl-benzenemethanol
  • 4-CHLOROBENZHYDROL pure
  • 4-Chloro-α-phenylbenzenemethanol
  • (p-Chlorophenyl)phenylmethanol
  • p-Chlorobenzohydrol
  • Phenyl(4-chlorophenyl)methanol
  • Meclizine Related Compound A (15 mg) (4-chlorobenzhydrol)
  • 4-CHLOROBENZHYDROL FOR SYNTHESIS
  • Buclizine HCl IMpurity-B(BP/EP)
  • Levocetrizine IMpurity
  • 4-Chloro Benzhydrol (Meclozine EP IMpurity B)
  • Meclozine EP IMpurity B (4-Chlorobenzhydrol)
  • BenzeneMethanol, 4-chloro-α-phenyl-
  • Meclozine impurity B
  • Cetirizine 4-Chlorobenzhydrol Impurity (USP)
  • Meclizine USP RC A
  • 4-Chlorobenzhydrol 98%
  • Buclizine EP Impurity B
  • (R)-(4-chlorophenyl)-phenylmethanol
  • Cetirizine Impurity L
  • Meclizine USP Related Compound A
  • Cetirizine Impurity I
  • 4-Chlorobenzhydrol >
  • Meclozine impurity B CRS
  • N-Methyl-2-(pyridin-2-yl)-N-[2-(pyr
  • Levocloperastine CBZ Racemate
  • Meclizine EP Impurity B
  • Meclozine EP Impurity B
  • Meclozine imp-B/4-Chlorobenzhydrol
  • Cetirizine 4-Chlorobenzhydrol Impurity (Meclizine Related Compound A)
  • Meclizine Related Compound A (Cetirizine 4-Chlorobenzhydrol Impurity)
  • Cetrizine 4-chlorobenzyhydrol Impurity
  • Cetirizine Impurity93
  • 4-ChlorobenzhydrolQ: What is 4-Chlorobenzhydrol Q: What is the CAS Number of 4-Chlorobenzhydrol Q: What is the storage condition of 4-Chlorobenzhydrol Q: What are the applications of 4-Chlorobenzhydrol
  • Chlorobenzhydrol
  • Cetirizine 4-Chlorobenzhydrol Impurity
  • Meclozine Dihydrochloride Impurity B
  • Meclozine EP Impurity B (Meclizine USP Related Compound A, 4-Chlorobenzhydrol)
  • Cinnarizine Impurity 12
  • Meclozine Dihydrochloride EP Impurity B
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