[1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-β-D-glucopyranosid

2415-24-9

CAS-Nr.: 2415-24-9

Bezeichnung:: [1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-β-D-glucopyranosid

Englisch Name:: Catalpol

Synonyma:: CATAPOL;CATALPOL;Catalpol-RM;catalpinoside;Catapol ,>=98%;Catalpol，Catalnol;CATALPOL WITH HPLC;Catalpol 2415-24-9;,6-beta,6a-alpha))-;Digitalis purpurea L

CBNumber:: CB6127844

Summenformel:: C15H22O10

Molgewicht:: 362.33

MOL-Datei:: 2415-24-9.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 267

[1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-β-D-glucopyranosid Eigenschaften

Schmelzpunkt:: 203-205°C

Siedepunkt:: 675.6±55.0 °C(Predicted)

Dichte: 1.72±0.1 g/cm3(Predicted)

storage temp.: Inert atmosphere,Store in freezer, under -20°C

L?slichkeit: DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)

Aggregatzustand: Solid

pka: 12.79±0.70(Predicted)

Farbe: White to Off-White

InChIKey: LHDWRKICQLTVDL-CLLMHHLUSA-N

LogP: -4.609 (est)

Sicherheit

Risiko- und Sicherheitserkl?rung
Gefahreninformationscode (GHS)

Kennzeichnung gef?hrlicher	Xi
R-S?tze:	36/37/38
S-S?tze:	26-36
WGK Germany	3
RTECS-Nr.	LZ5776816
HS Code	29389090
Toxizit?t	mouse,LD,intravenous,> 2500mg/kg (2500mg/kg),Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 64, Pg. 93, 1968.

Bildanzeige (GHS)

Alarmwort

Warnung

Gefahrenhinweise

Code	Gefahrenhinweise	Gefahrenklasse	Abteilung	Alarmwort	Symbol	P-Code
H315	Verursacht Hautreizungen.	Hautreizung	Kategorie 2	Warnung	src="/GHS07.jpg" width="20" height="20" />	P264, P280, P302+P352, P321,P332+P313, P362
H319	Verursacht schwere Augenreizung.	Schwere Augenreizung	Kategorie 2	Warnung	src="/GHS07.jpg" width="20" height="20" />	P264, P280, P305+P351+P338,P337+P313P
H335	Kann die Atemwege reizen.	Spezifische Zielorgan-Toxizit?t (einmalige Exposition)	Kategorie 3 (Atemwegsreizung)	Warnung	src="/GHS07.jpg" width="20" height="20" />

Sicherheit

P261	Einatmen von Staub vermeiden.
P264	Nach Gebrauch gründlich waschen.
P264	Nach Gebrauch gründlich waschen.
P271	Nur im Freien oder in gut belüfteten R?umen verwenden.
P280	Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P302+P352	BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.
P305+P351+P338	BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

[1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-β-D-glucopyranosid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Beschreibung

Catalpol is an iridoid glycoside that has been isolated from R. glutinosa and has diverse biological activities, including anti-apoptotic, pro-angiogenic, and radioprotective properties. It protects against mitochondrial pathway-dependent apoptosis in PC12 rat adrenal pheochromocytoma cells and H9c2 rat embryonic ventricular myocardial cells when used at a concentration of 10 μM. Catalpol pretreatment reduces apoptosis and improves viability in AHH-1 human lymphocyte cells exposed to ionizing radiation and reduces intestinal damage induced by radiation in mice when used at concentrations and doses ranging from of 25 to 100 μg/ml and 25 to 100 mg/kg, respectively. In a rat model of stroke, catalpol (5 mg/kg, i.p.) increases the expression of erythropoietin and VEGF and improves angiogenesis in the brain.

Chemische Eigenschaften

Light brown powder

Verwenden

Catapol is an iridoid glucoside that has been shown to alleviate neuropathic pain.

[1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-β-D-glucopyranosid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Pentan-3-on

Downstream Produkte

[1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-β-D-glucopyranosid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 267)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20284	58
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29880	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3772	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	sales@dolonchem.com	CHINA	2972	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
NanJing Spring & Autumn Biological Engineering CO., LTD.	+8613815430202	sale02@cqherb.com	CHINA	376	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58

2415-24-9([1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-β-D-glucopyranosid)Verwandte Suche:

Salicyls?ure Zitronensure 4-Hydroxy-3-methoxyzimtsure β-D-Glucopyranosid, 1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, 6-(3-Phenyl-2-propenoat), [1aS-[1aα,1bβ,2β(E),5aβ,6β,6aα- [1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-β-D-glucopyranosid

CATALPOL
,6-beta,6a-alpha))-
beta-d-glucopyranoside,1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)
catalpinoside
de(p-hydroxybenzoyl)catalposide
des-p-hydroxybenzoyl-catalposid
oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl,(1as-(1a-alpha,1b-beta,2-beta,5a-beta
[1aS-(1aalpha,1bbeta,2beta,5abeta,6beta,6a.alpha.)]-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-beta-D-glucopyranoside
.beta.-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno4,5cyclopenta1,2-cpyran-2-yl
CATALPOL WITH HPLC
1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl
β-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-
Catalpol，Catalnol
[(1aS)-1a,1bα,2,5aα,6,6aβ-Hexahydro-6α-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2α-yl]β-D-glucopyranoside
Catapol ,>=98%
(1AS-(1aα,1bβ,2β,5aβ,6β,6aα-))1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxyMethyl)oxireno(4,5)cyclopenta(1,2-c)-pyran-2-yl-beta-D-glucopyranoside
(1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-β-D-glucopyranoside
Digitalis purpurea L
Catalpol 2415-24-9
Catalpol, ≥97%(HPLC)
(3R,4S,5S,6R)-2-(((1aS,1bS,2S,5aR,6S,6aS)-6-Hydroxy-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[2',3':4,5]cyclopenta[1,2-c]pyran-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
β-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl
(2S,3R,4S,5S,6R)-2-[[(1aS,1bS,2S,5aR,6S,6aS)-6-hydroxy-1a-(hydroxymethyl)-2,5a,6,6a-tetrahydro-1bH-oxireno[5,6]cyclopenta[1,3-c]pyran-2-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
(2S,3R,4S,5S,6R)-2-(((1aS,1bS,2S,5aR,6S,6aS)-6-Hydroxy-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[2',3':4,5]cyclopenta[1,2-c]pyran-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
CATAPOL
(2S, 3R, 4S, 5S, 6R) -2- (((1aS, 1bS, 2S, 5aR, 6S, 6aS) -6-hydroxy-1a - (hydroxymethyl) -1a, 1b, 2,5a, 6,6a - hexahydroepoxyethano [2 ', 3': 4,5] cyclopentadieno [1,2-c] pyran-2-yl) oxy) -6- (hydroxymethyl) tetrahydro-2H-pyran-3,4,5-triol
(2S,3R,4S,5S,6R)-2-(((1aS,1bS,2S,5aR,6S,6aS)-6-Hydroxy-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[2',3':4,5]cyclopenta[1,2-c]pyran-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Catalpol-RM
2415-24-9
chemical reagent
pharmaceutical intermediate
phytochemical
reference standards from Chinese medicinal herbs (TCM).
standardized herbal extract
Inhibitors
Iridoids

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