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Cyanocobalamin

Vitamin B12 Struktur
68-19-9
CAS-Nr.
68-19-9
Bezeichnung:
Cyanocobalamin
Englisch Name:
Vitamin B12
Synonyma:
CYANOCOBALAMIN;Vb12;METHYLCOBALAMIN;CYANOCOBALAMINE;hemomin;cyanocobalamin (b12);COBALAMINE;hydroxycobalamin chloride;VIT B12;lldfactor
CBNumber:
CB6126463
Summenformel:
C63H88CoN14O14P
Molgewicht:
1355.37
MOL-Datei:
68-19-9.mol

Cyanocobalamin Eigenschaften

Schmelzpunkt:
>300°C
Siedepunkt:
>300 °C
alpha 
23656 -59 ± 9° (dil aq soln)
Flammpunkt:
9℃
storage temp. 
2-8°C
L?slichkeit
Sparingly soluble in water and in ethanol (96 per cent), practically insoluble in acetone. The anhydrous substance is very hygroscopic.
Aggregatzustand
Crystalline Powder or Crystals
pka
pKa 3.28±0.04(H2O,D2O t=23±0.5 Iunspeci?ed) (Uncertain)
Farbe
Red to dark red
Geruch (Odor)
dark red cryst. or powd., odorless and tasteless
Wasserl?slichkeit
Soluble
Sensitive 
Hygroscopic
Merck 
14,10014
BRN 
4122889
Expositionsgrenzwerte
NIOSH: IDLH 25 mg/m3
Stabilit?t:
Hygroscopic. Keep cold and dry.
InChIKey
RMRCNWBMXRMIRW-WZHZPDAFSA-L
LogP
3.570 (est)
EPA chemische Informationen
Vitamin B12 (68-19-9)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher
HS Code  2936260000
Giftige Stoffe Daten 68-19-9(Hazardous Substances Data)
Toxizit?t LD50 intravenous in mouse: 2gm/kg
Bildanzeige (GHS) GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H225 Flüssigkeit und Dampf leicht entzündbar. Entzündbare Flüssigkeiten Kategorie 2 Achtung GHS hazard pictogramssrc="/GHS02.jpg" width="20" height="20" /> P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H370 Sch?digt die Organe. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 1 Achtung GHS hazard pictogramssrc="/GHS08.jpg" width="20" height="20" /> P260, P264, P270, P307+P311, P321,P405, P501
Sicherheit
P210 Von Hitze, hei?en Oberfl?chen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen.
P260 Dampf/Aerosol/Nebel nicht einatmen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P301+P310 BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P311 GIFTINFORMATIONSZENTRUM/Arzt anrufen.

Cyanocobalamin Chemische Eigenschaften,Einsatz,Produktion Methoden

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Chemische Eigenschaften

Dark red, crystalline powder or dark red crystals.

History

VITAMIN B12 (Cobalamin), Sometimes also called cyanocobalamin, this vitamin is one of the more recent of the major B complex vitamins to be fully identified, with its structure not definitized (by Hodkin et al.)

Verwenden

Prototype of the family of naturally occurring cobalt coordination compounds knows as corrinoids. Analogs of vitamin B12 which differ only in the β-ligand of the cobalt are termed cobalamins. Synthesi zed almost exclusively by bacteria. Dietary sources include fish, meat, liver, and dairy products; plants have little or no cobalamins. Converted by the body into its bioactive forms, methylcobalamin and cobamamide, which serve as enzyme cofactors. Severe deficiency may result in megaloblastic anemia and/or neurological impairment.

Vorbereitung Methode

Vitamin B12 dietary supplements are often prepared commercially by the fermentation of S. griseus, S. aureofaciens, Propionibacterium; or as a by-product of antibiotic production.

Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Cyanocobalamin, also known as vitamin B12, belongs to a group of organic compounds important for the normal growth and development of human and animal bodies. It is used for the treatment of trigeminal neuralgia and multiple sclerosis.

Health Hazard

Deficiency diseases or disorders include retarded growth; pernicious anemia; megaloblastic anemia; macrocytic, hyperchromic anemia; glossitis; spinal cord degeneration; and sprue.

Biologische Aktivit?t

Principal physiological functions include: (1) Coenzyme in nucleic acid, protein, and lipid synthesis; (2) maintains growth; (3) participates in methylations; (4) maintains epithelial cells and nervous system (myelin sheath); (5) erythropoiesis (with folic acid); (6) leukopoiesis.

Sicherheitsprofil

Poison by subcutaneous route. Moderately toxic by intraperitoneal route. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of POx and NOx. See also COBALT COMPOUNDS.

Cyanocobalamin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Cyanocobalamin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 998)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
APOLLO HEALTHCARE RESOURCES
+6596580999
sales@apollo-healthcare.com.sg Singapore 399 58
Siyang Liaoning Biochemical Products Co. Ltd
+86-15221114306; +8615221114306
2594582574@qq.com China 561 58
Baoji Guokang Bio-Technology Co., Ltd.
0917-3909592 13892490616
gksales1@gk-bio.com China 9312 58
TAIZHOU YUXIN BIOTECHNOLOGY CO,.LTD
+86-576-88902229;+86-0576-88902229 +8613968687450
yuxin@yuxchem.com China 167 58
Watson Biotechnology Co.,Ltd
+86-18186686046 +86-18186686046
sales01@watsonbiotech.cn China 5841 58
Shandong Deshang Chemical Co., Ltd.
+86-0531-8875-2665 +8613153039501
info@deshangchem.com China 662 58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
+8615350851019
admin@86-ss.com China 1001 58
Guangzhou Tosun Pharmaceutical Ltd
+86-020-61855200-902 +8618124244216
info@upharm.cn China 831 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-81148696 +86-15536356810
1022@dideu.com China 3882 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578
sales@hbmojin.com China 12835 58

68-19-9(Cyanocobalamin)Verwandte Suche:


  • hepagon
  • hepavis
  • magravon
  • megalovel
  • nagravon
  • normocytin
  • pernaemon
  • pernipuron
  • plecyamin
  • rebramin
  • rhodacryst
  • rubesol
  • rubramin
  • rubraminpc
  • rubripca
  • rubrocitol
  • sytobex
  • terwithcobinamidecyanidehydroxide,innersalt
  • vibalt
  • virubra
  • vitaminb12complex
  • vitaminb12preparation
  • vitarubin
  • vita-rubra
  • vitral
  • ylbenzimidazole,innersalt
  • CYANOCOBALAMIN USP CRYSTAL
  • a-(5,6-dimethylbenzimidazolyl)-cobalamidecyanide
  • α-(5,6-Dimethylbenzimidazolyl)cyanocobamide, CN-Cbl, Cyanocob(III)alamin, Cyanocobalamin
  • ANTIANEMIC VITAMIN B
  • EXTRINSIC FACTOR
  • CYTACON
  • CYTAMEN
  • Vitamin B12, USP grade
  • 5,6-dimethyl-1-(3-o-phosphono-alpha-d-ribofuranosyl)-1h-benzimidazolmonoes
  • 5,6-dimethylbenzimidazolylcobamidecyanide
  • alpha-5,6-dimethyl-1h-benzimidazolyl-cobamidcyanide
  • anacobin
  • betalin-12
  • betalin12crystalline
  • betaline-12
  • betolvex
  • bevatine-12
  • b-twelve
  • b-twelveora
  • byladoce
  • cabadonm
  • cn-b12
  • cobadoceforte
  • cobalamin,cyanide
  • cobalin
  • cobamin
  • cobinamide,cyanidehydroxide,dihydrogenphosphate(ester),innersalt,3’-est
  • cobinamide,cyanidephosphate3’-esterwith5,6-dimethyl-1-alpha-d-ribofuranos
  • cobione
  • cotel
  • covit
  • crystamin
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