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3,5-dihydroxy-3-methyl-Pentanoic acid

3,5-dihydroxy-3-methyl-Pentanoic acid Struktur
150-97-0
CAS-Nr.
150-97-0
Englisch Name:
3,5-dihydroxy-3-methyl-Pentanoic acid
Synonyma:
MVS;MK 91;(±)-MVA-Li;rac.-MVA-Li;Hiochic Acid;Mevalonic acid;RS-Mevalonic Acid;D,L-Mevalonic Acid;Tedizolid Impurity 85;(RS)-Mevalonic acid lithium salt
CBNumber:
CB61236091
Summenformel:
C6H12O4
Molgewicht:
148.16
MOL-Datei:
150-97-0.mol

3,5-dihydroxy-3-methyl-Pentanoic acid Eigenschaften

storage temp. 
2-8°C
L?slichkeit
Soluble in DMSO
Aggregatzustand
Solid
Siedepunkt:
364.1±32.0 °C(Predicted)
Dichte
1.263±0.06 g/cm3(Predicted)
Schmelzpunkt:
151-152 °C(Solv: benzene (71-43-2))
pka
4.33±0.10(Predicted)
Farbe
White to off-white
Concentration
0.1 mCi/ml
Specific Activity
10-20 Ci/mmol
Solvent
Ethanol:0.15N NH4OH (1:1)
EPA chemische Informationen
Pentanoic acid, 3,5-dihydroxy-3-methyl- (150-97-0)

Sicherheit

WGK Germany  3
Giftige Stoffe Daten 150-97-0(Hazardous Substances Data)

3,5-dihydroxy-3-methyl-Pentanoic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Precursor in the biosynthesis of cholesterol. Occurs in equilibrium with the d-lactone

Definition

Anorganic acid, it is an intermediate in the biosyn-thesis of squalene, cholesterol, and coenzyme q inplants and animals.

Biosynthese

Mevalonic acid is the primary precursor of an the terpenoids and steroids biosynthesised by plants. It is derived from acetyl CoA through the intermediate formation of acetoacetyl CoA and 3-hydroxy-3-methylglutaryl CoA (HMG CoA), these reactions being catalysed by acetyl CoA acetyltransferase and HMG CoA synthase, respectively. Reduction of HMG CoA, catalysed by HMG CoA reductase, gives mevalonic acid.
The biosynthesis of mevalonic acid
Before the pathway can continue, mevalonic acid must be catalytically phosphorylated by ATP and mevalonic acid kinase. Mevalonic acid kinase activity has been detected in many plants and has been found to be inhibited by such products of the acetate-mevalonate pathway as geranyl, farnesyl, geranylgeranyl and phytyl pyrophosphates. Thus, phosphorylation of mevalonic acid is a primary point at which control of terpenoid and steroid biosynthesis operates. Phosphorylation leads first to the mono- and then to the pyrophosphate. The second phosphorylation is catalysed by phosphomevalonate kinase.

3,5-dihydroxy-3-methyl-Pentanoic acid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


3,5-dihydroxy-3-methyl-Pentanoic acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 20)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Dideu Medichem Co. Ltd
+86-29-81148696 +86-15536356810
1022@dideu.com China 3882 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38631 58
Shanghai Macklin Biochemical Co.,Ltd. 15221275939 15221275939
shenlinxing@macklin.cn China 16166 55
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51456 80
Beijing OKA biological technology co., LTD 010-010-010-62971590 18548936886
jack@oka-vip.com China 6897 58
Guangdong wengjiang Chemical Reagent Co., Ltd. 0751-2815688 13927872512
3007421951@qq.com China 10057 58
Energy Chemical 021-58432009 400-005-6266
marketing1@energy-chemical.com China 44807 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24644 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 18621169109
market03@meryer.com China 27987 58

  • 3,4-Dihydroxy-3-methylpentanoic acid
  • 3,5-dihydroxy-3-methyl-Pentanoic acid
  • Mevalonic acid
  • 2,4-Dideoxy-3-C-methylpentonic Acid
  • 3,5-Dihydroxy-3-methylvaleric Acid
  • D,L-Mevalonic Acid
  • Hiochic Acid
  • MK 91
  • MVS
  • RS-Mevalonic Acid
  • (±)-MVA-Li
  • (RS)-Mevalonic acid lithium salt
  • Lithium (±)-3,5-dihydroxy-3-methyl-pentanoate
  • Lithium (±)-3,5-dihydroxy-3-methyl-valerate
  • rac.-MVA-Li
  • Pentanoic acid, 3,5-dihydroxy-3-methyl-
  • Tedizolid Impurity 85
  • 150-97-0
  • All Aliphatics
  • Aliphatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
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