BLU-945

2660250-10-0

CAS-Nr.: 2660250-10-0

Englisch Name:: BLU-945

Synonyma:: BLU-945;N-[2-[(3S,4R)-3-fluoro-4-methoxy-1-piperidyl]pyrimidin-4-yl]-5-isopropyl-8-[(2R,3S)-2-methyl-3-(methylsulfonylmethyl)azetidin-1-yl]isoquinolin-3-amine;N-[2-[(3S,4R)-3-Fluoro-4-methoxy-1-piperidyl]-4-pyrimidinyl]-5-isopropyl-8-[(2R,3S)-2-methyl-3-[(methylsulfonyl)methyl]-1-azetidinyl]isoquinolin-3-amine;N-(2-((3S,4R)-3-Fluoro-4-methoxypiperidin-1-yl)pyrimidin-4-yl)-5-isopropyl-8-((2R,3S)-2-methyl-3-((methylsulfonyl)methyl)azetidin-1-yl)isoquinolin-3-amine;N-{2-[(3S,4R)-3-fluoro-4-methoxypiperidin-1-yl]pyrimidin-4-yl}-8-[(2R,3S)-3-(methanesulfonylmethyl)-2-methylazetidin-1-yl]-5-(propan-2-yl)isoquinolin-3-amine;3-Isoquinolinamine, N-[2-[(3S,4R)-3-fluoro-4-methoxy-1-piperidinyl]-4-pyrimidinyl]-5-(1-methylethyl)-8-[(2R,3S)-2-methyl-3-[(methylsulfonyl)methyl]-1-azetidinyl]-

CBNumber:: CB610776751

Summenformel:: C28H37FN6O3S

Molgewicht:: 556.7

MOL-Datei:: 2660250-10-0.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 63

BLU-945 Eigenschaften

Siedepunkt:: 784.6±70.0 °C(Predicted)

Dichte: 1.32±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

Aggregatzustand: Solid

pka: 7.87±0.10(Predicted)

Farbe: Light yellow to yellow

InChIKey: LIMFPAAAIVQRRD-MCEZSBKONA-N

SMILES: C(C1=CC=C(N2C[C@H](CS(=O)(=O)C)[C@H]2C)C2C=NC(NC3C=CN=C(N4CC[C@@H](OC)[C@@H](F)C4)N=3)=CC1=2)(C)C |&1:7,13,28,31,r|

Sicherheit

BLU-945 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

BLU-945 is a potent, highly selective, reversible, and orally active epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). It can effectively inhibit EGFR with L858R and/or exon 19 deletion mutation, T790M mutation, and C797S mutation. BLU-945 can be used for research on lung cancer, including non-small cell lung cancer (NSCLC)[1].

Nebenwirkungen

According to clinical studies of BLU-945, common side effects of BLU-945 monotherapy include: rash, diarrhoea, nausea, vomiting, headache, dry skin, onychomycosis, and elevated alanine aminotransferase and aspartate aminotransferase. Common side effects of the combination of BLU-945 and ositinib include: headache, nausea, fatigue, decreased appetite, vomiting, diarrhoea, dry skin, acne-like dermatitis and onychomycosis.

BLU-945 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

BLU-945 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 63)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	5221	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	17777	58
Nanjing Shizhou Biotechnology Co., Ltd	+86-15850508050 +86-15850508050	sean.lv@synzest.com	China	323	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10473	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3135	58
Hebei Miaoyin Technology Co.,Ltd	+86-17367732028 +86-17367732028	kathy@hbyinsheng.com	China	3512	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43340	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52924	58
Taizhou Creating Bio-pharm co., ltd.	+8613586099526	post@creatingbiopharm.com	China	217	58

BLU-945
N-[2-[(3S,4R)-3-Fluoro-4-methoxy-1-piperidyl]-4-pyrimidinyl]-5-isopropyl-8-[(2R,3S)-2-methyl-3-[(methylsulfonyl)methyl]-1-azetidinyl]isoquinolin-3-amine
N-[2-[(3S,4R)-3-fluoro-4-methoxy-1-piperidyl]pyrimidin-4-yl]-5-isopropyl-8-[(2R,3S)-2-methyl-3-(methylsulfonylmethyl)azetidin-1-yl]isoquinolin-3-amine
3-Isoquinolinamine, N-[2-[(3S,4R)-3-fluoro-4-methoxy-1-piperidinyl]-4-pyrimidinyl]-5-(1-methylethyl)-8-[(2R,3S)-2-methyl-3-[(methylsulfonyl)methyl]-1-azetidinyl]-
N-(2-((3S,4R)-3-Fluoro-4-methoxypiperidin-1-yl)pyrimidin-4-yl)-5-isopropyl-8-((2R,3S)-2-methyl-3-((methylsulfonyl)methyl)azetidin-1-yl)isoquinolin-3-amine
N-{2-[(3S,4R)-3-fluoro-4-methoxypiperidin-1-yl]pyrimidin-4-yl}-8-[(2R,3S)-3-(methanesulfonylmethyl)-2-methylazetidin-1-yl]-5-(propan-2-yl)isoquinolin-3-amine
2660250-10-0
blu945

成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天