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SIS3

SIS3 Struktur
521984-48-5
CAS-Nr.
521984-48-5
Englisch Name:
SIS3
Synonyma:
SIS3;CS-2236;SIS3 HCl;Caneritinib;SIS3 (SIS 3;SIS3 hydrochloride;SIS 3 HCL;SIS-3 HCL;Caneritinib(CI-1033);1,2,3,4-Tetrahydro-6,7-dimethoxy-2-[(2E)-3-(1-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-1-oxo-2-propenyl]-isoquinoline hydrochloride;(2E)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-propenone hydrochloride
CBNumber:
CB5973013
Summenformel:
C28H27N3O3HCl
Molgewicht:
0
MOL-Datei:
521984-48-5.mol

SIS3 Eigenschaften

Schmelzpunkt:
>161°C (dec.)
storage temp. 
2-8°C
L?slichkeit
H2O: <2mg/mL
Aggregatzustand
powder
Farbe
yellow
InChIKey
CDKIEBFIMCSCBB-CALJPSDSSA-N

Sicherheit

WGK Germany  3

SIS3 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Sugar insensitive 3 (SIS3) has been used as smad3?inhibitor in various cells.

Biochem/physiol Actions

Sugar insensitive 3 (SIS3) promotes drug-induced apoptosis and hinders the function of adenosine triphosphate (ATP)-binding cassette (ABC) transporter (ABCB1) and ABCG2. It resensitizes ABCB1 and ABCG2 overexpressed in cancerous cells, which contributes to chemotherapeutics.

SIS3 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


SIS3 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 87)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32951 60
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29814 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32072 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471
sales@sarms4muscle.com China 10473 58
Alfa Chemistry

Info@alfa-chemistry.com United States 24072 58
InvivoChem
+1-708-310-1919 +1-13798911105
sales@invivochem.cn United States 6391 58
Henan Aochuang Chemical Co.,Ltd.
+86-0371-63689365 +8618638391208
sales@aochuangchem.com China 9237 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38465 58
LEAPCHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 43340 58

  • SIS3
  • (2E)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-propenone hydrochloride
  • 2-Propen-1-one,1-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-,hydrochloride (1:1), (2E)-
  • SIS3 hydrochloride
  • SIS3 HCl
  • 1,2,3,4-Tetrahydro-6,7-dimethoxy-2-[(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-1-oxo-2-propenyl]-isoquinoline Monohydrochloride
  • Caneritinib(CI-1033)
  • SIS 3 HCL;SIS-3 HCL
  • 1,2,3,4-Tetrahydro-6,7-dimethoxy-2-[(2E)-3-(1-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-1-oxo-2-propenyl]-isoquinoline hydrochloride
  • Caneritinib
  • CS-2236
  • SIS3 (SIS 3
  • (E)-1-[6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl]-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one Hydrochloride
  • myofibroblast,inhibit,TGF-β1,TGF-beta/Smad,(E)SIS3,Smad3,(E)-SIS3,Transforming growth factor beta,fibroblasts,differentiation,(E) SIS3,phosphorylation,(E)-SIS-3,Inhibitor
  • 521984-48-5
  • C28H27N3O3HCl
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