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4,4'-Propylenbis(piperazin-2,6-dion)

4,4'-propylenebis(piperazine-2,6-dione) Struktur
21416-67-1
CAS-Nr.
21416-67-1
Bezeichnung:
4,4'-Propylenbis(piperazin-2,6-dion)
Englisch Name:
4,4'-propylenebis(piperazine-2,6-dione)
Synonyma:
Troxozone;RAZOXANUM;Propyliminum;rac-Dexrazoxane;4,4'-(Propane-1,2-diyl);bis(piperazine-2,6-dione);-propylenebis(piperazine-2,6-dione);4,4'-propylenebis(piperazine-2,6-dione);4,4'-Propane-1,2-diyldipiperazine-2,6-dione;4,4'-(1-Methylethylene)bis(2,6-piperazinedione)
CBNumber:
CB5918838
Summenformel:
C11H16N4O4
Molgewicht:
268.27
MOL-Datei:
21416-67-1.mol

4,4'-Propylenbis(piperazin-2,6-dion) Eigenschaften

Schmelzpunkt:
237-239°
Siedepunkt:
411.43°C (rough estimate)
Dichte
1.2576 (rough estimate)
Brechungsindex
1.6081 (estimate)
storage temp. 
Inert atmosphere,2-8°C
L?slichkeit
DMSO: soluble40mg/mL
Aggregatzustand
solid
pka
11.00±0.20(Predicted)
Farbe
White to off-white
Wasserl?slichkeit
3g/L(25 ºC)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
WGK Germany  3
RTECS-Nr. TL6389900
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

4,4'-Propylenbis(piperazin-2,6-dion) Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Razoxane is an inhibitor of Topo II.

Sicherheitsprofil

Suspected human carcinogen producing leukemia and skin tumors. Moderately toxic by intraperitoneal route. Human effects: normocytic anemia and thrombocytopenia. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

4,4'-Propylenbis(piperazin-2,6-dion) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

4,4'-Propylenbis(piperazin-2,6-dion) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 40)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32957 60
Hubei xin bonus chemical co. LTD 		86-13657291602
linda@hubeijusheng.com CHINA 22963 58
Alchem Pharmtech,Inc. 		8485655694
sales@alchempharmtech.com United States 63687 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695
 laboratory@coreychem.com China 30239 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250
 1026@dideu.com China 22784 58
Dayang Chem (Hangzhou) Co.,Ltd. 		571-88938639 +8617705817739
 info@dycnchem.com China 52849 58
PT CHEM GROUP LIMITED 		+86-85511178; +86-85511178;
 peter68@ptchemgroup.com China 35425 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490
 info@gihichemicals.com China 49978 58
Guangzhou Tosun Pharmaceutical Limited 		+8618922120635
 sales@toref-standards.com China 998 58
  • 4,4'-propylenebis(piperazine-2,6-dione)
  • 4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione)
  • RAZOXANUM
  • 4,4'-(1-Methylethylene)bis(2,6-piperazinedione)
  • 4,4'-Propane-1,2-diyldipiperazine-2,6-dione
  • Propyliminum
  • 4-[3-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione
  • Troxozone
  • 4,4'-(Propane-1,2-diyl)
  • bis(piperazine-2,6-dione)
  • -propylenebis(piperazine-2,6-dione)
  • 4,4'-propylenebis(piperazine-2,6-dione) USP/EP/BP
  • 4,5,9,10-Pyrenetetrone,2,7-bis(1,6-dimethylethyl)-
  • rac-Dexrazoxane
  • ICRF 159,ICRF159,ICRF-159,Topoisomerase II Inhibitor,Razoxane,RCC,Inhibitor,Topoisomerase,renal cell carcinoma,inhibit
  • 4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione)
  • 21416-67-1
  • Angiogenesis and metastasis.
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