AG 1295 Chemische Eigenschaften,Einsatz,Produktion Methoden

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Beschreibung

Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors specific for platelet-derived growth factor (PDGF) receptor kinase could help in the treatment of atherosclerosis, restenosis, pulmonary fibrosis, and gliomas. AG-1295 is a quinoxaline-type tyrphostin that acts as a potent and selective inhibitor of PDGF receptor kinase in vitro and in Swiss 3T3 cells (IC₅₀s range from 0.3-1 μM). It inhibits PDGF-stimulated DNA synthesis with an IC₅₀ value of 2.5 μM without affecting activity of the EGF receptor.

Verwenden

AG-1295 is a protein tyrosine kinase inhibitor. Antiproliferative agent used in the treatment of atherosclerosis, pulmonary fibrosis, and gliomas.

AG 1295 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

AG 1295 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29879	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	22787	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38631	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52924	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Spectrum Chemical Manufacturing Corp.	021-021-021-67601398-809-809-809 15221380277	marketing_china@spectrumchemical.com	China	9658	60
Struchem Co., Ltd.	0512-0512-63009836 15365350169	helen@struchem.com	China	3984	60

71897-07-9()Verwandte Suche:

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• 6,7-DIMETHYL-2-PHENYLQUINOXALINE
• AG 1295
• TYROPHOSTIN AG1295
• TYRPHOSTIN AG 1295
• AG 1295 PLATELET-DERIVED GROW
• TYRPHOSTIN AG 1295, 99+%
• Quinoxaline, 6,7-dimethyl-2-phenyl-
• AG-1295 (NSC 380341
• NSC 380341
• AG 1295 USP/EP/BP
• Platelet-derived growth factor receptor,RTK,AG 1295,inhibit,PDGF-receptor,AG-1295,autophosphorylation,Inhibitor,AG1295,PDGFR
• AG 1295, 10 mM in DMSO
• 71897-07-9
• 70897-07-9
• Cell Signaling and Neuroscience
• Cell Biology
• BioChemical
• Kinase/Phosphatase Biology
• Receptor Tyrosine Kinase Inhibitors
• Platelet Derived Growth Factor Receptor (PDGFR)