CP-424,174
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CP-424,174 Eigenschaften
- Dichte
- 1?+-.0.06 g/cm3(Predicted)
- storage temp.
- room temp
- L?slichkeit
- DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:5): 0.16 mg/ml
- pka
- 4.67±0.10(Predicted)
- Aggregatzustand
- powder
- Farbe
- white to beige
Sicherheit
CP-424,174 Chemische Eigenschaften,Einsatz,Produktion Methoden
Biochem/physiol Actions
CP-424,174 is a cytokine release inhibitory drugs (CRID) that inhibits the post-translational processing and secretion of IL-1b in response to LPS and ATP in human monocytes. It is quite possible that similarly to CP-456,773 (termed CRID3), CP-424,174 inhibits both NLRP3 and AIM2 inflammasomes by preventing ASC oligomerisation.CP-424,174 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
CP-424,174 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 37)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 33024 | 60 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32159 | 58 |
TargetMol Chemicals Inc. | |
support@targetmol.com | United States | 38630 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 |
masar@topule.com | China | 8467 | 58 |
Aladdin Scientific | |
tp@aladdinsci.com | United States | 57505 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51456 | 80 |
Zhengzhou Alfachem Co.,Ltd. | 0371-53778726 18003825608 |
liuxiaoyan@alfachem.cn | China | 1993 | 58 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9804 | 58 |
Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 |
sales@rechemscience.com | China | 2990 | 58 |
Shanghai Chaolan Chemical Technology Center | 021-QQ:65489617 15618227136 |
Sales@ATKchemical.com | China | 9014 | 58 |
- CP-424,174
- N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide
- Benzenesulfonamide, N-[[[4-chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)-
- CP-424,174 >=98% (HPLC)
- N-((4-Chloro-2,6-diisopropylphenyl)carbamoyl)-3-(2-hydroxypropan-2-yl)benzenesulfonamide
- CP424174,IL-1β,NLRP3,Inhibitor,CP 424174,CP-424174,Inflammasome,inhibit,NOD-like Receptor (NLR)
- CP 424174, 10 mM in DMSO
- 210825-31-3