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943319-87-7

943319-87-7 Struktur
943319-87-7
CAS-Nr.
943319-87-7
Englisch Name:
943319-87-7
Synonyma:
AP24567;AP-24567;Ponatinib N-Desmethyl;N-Desmethyl ponatinib;Ponatinib N-Desmethyl Analog;Ponatinib Active Metabolite A;Ponatinib Active Metabolite AP24567(M42);Benzamide, 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-(1-piperazinylmethyl)-3-(trifluoromethyl)phenyl]-
CBNumber:
CB54660663
Summenformel:
C28H25F3N6O
Molgewicht:
518.53
MOL-Datei:
943319-87-7.mol

943319-87-7 Eigenschaften

Dichte
1.32±0.1 g/cm3(Predicted)
L?slichkeit
DMSO (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
12.99±0.70(Predicted)
Farbe
Pale Yellow to Light Yellow

Sicherheit

943319-87-7 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Ponatinib Active Metabolite AP24567(M42) is a research reagent applied in pharmaceuticals and cancer treatment. Ponatinib Active Metabolite AP24567(M42) is an analog of Ponatinib (P688250) which is a tyrosine kinase inhibitors (TKI) and used to treat chronic myeloid leukemia (CML) (1,2,3). Ponatinib (P688250) is also used in combination with other drugs, such as forskolin, to combat TKI resistance in patient with CML (3), targeted drug in small-cell lung cancer. Potent FAK inhibitor. FGFR/VEGFR/Bcr-Abl inhibitor It is a COVID19-related research product.

943319-87-7 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

943319-87-7 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 17)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Moxin Chemicals 		+8617320513646
 mike@molcoo.com China 9457 58
QUALITY CONTROL SOLUTIONS LTD. 		0755-66853366; 13670046396
 ORDERS@QCSRM.COM China 24342 58
Beijing Comparison Pharmaceutical Technology Co., Ltd 010-010-52878169 15801002657
 sales@bjcomparison.com China 5004 58
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656
 greensnown@163.com China 9906 50
Nanjing XiZe Biotechnology CO., Ltd. 025-66023220 0086-15250997978
 1511893459@qq.com China 7891 55
Shanghai CR Corporation Limited 021-80270511; 4006653949
 fred.wen@crcorporation.cn China 10044 58
TOSUN PHARM 020-61855200 13326451905
 260366801@qq.com China 7796 58
Beijing xinyanhui pharmaceutical research and development co., LTD 13969155946
 1461866103@qq.com China 16111 58
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822
 czbjpharma@126.com China 18478 58
  • N-Desmethyl ponatinib
  • Ponatinib N-Desmethyl
  • Benzamide, 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-(1-piperazinylmethyl)-3-(trifluoromethyl)phenyl]-
  • Ponatinib Active Metabolite AP24567(M42)
  • AP24567
  • AP-24567
  • Ponatinib Active Metabolite A
  • Ponatinib N-Desmethyl Analog
  • 943319-87-7
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