Boc-D-Ser(Bzl)-OH
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- CAS-Nr.
- 47173-80-8
- Englisch Name:
- Boc-D-Ser(Bzl)-OH
- Synonyma:
- O-BENZYL-N-(TERT-BUTOXYCARBONYL)-D-SERINE;BOC-SER(BZL)-OH;BOC-SER(BZL);BOC-D-SER(BZL);BOC-O-BENZYL-L-SERINE;(R)-3-(benzyloxy)-2-((tert-butoxycarbonyl)aMino)propanoic acid;(2R)-3-(benzyloxy)-2-{[(tert-butoxy)carbonyl]amino}propanoic acid;BOC-L-SER(BZL);(2R)-3-(benzylox;BOC-D-SER(BZL)-OH
- CBNumber:
- CB5438415
- Summenformel:
- C15H21NO5
- Molgewicht:
- 295.33
- MOL-Datei:
- 47173-80-8.mol
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Boc-D-Ser(Bzl)-OH Eigenschaften
- Schmelzpunkt:
- 58-60 °C(lit.)
- alpha
- -19 º (c=2 80% alcohol)
- Siedepunkt:
- 437.02°C (rough estimate)
- Dichte
- 1.1454 (rough estimate)
- Brechungsindex
- -20 ° (C=2, 80% EtOH)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- almost transparency in Methanol
- pka
- 3.53±0.10(Predicted)
- Aggregatzustand
- Powder
- Farbe
- White
- BRN
- 2665080
- InChI
- InChI=1S/C15H21NO5/c1-15(2,3)21-14(19)16-12(13(17)18)10-20-9-11-7-5-4-6-8-11/h4-8,12H,9-10H2,1-3H3,(H,16,19)(H,17,18)/t12-/m1/s1
- InChIKey
- DMBKPDOAQVGTST-GFCCVEGCSA-N
- SMILES
- C(O)(=O)[C@@H](COCC1=CC=CC=C1)NC(OC(C)(C)C)=O
- CAS Datenbank
- 47173-80-8(CAS DataBase Reference)
Boc-D-Ser(Bzl)-OH Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
White crystalline powder
Biologische Aktivit?t
Boc-O-benzyl-D-serine is an inhibitor of the uptake of galactose and its derivatives. It has potent inhibitory activity against the uptake of galactose, glucose, and lactose. This drug is also effective in inhibiting the uptake of tetrazole, a substance that inhibits glycolysis. Boc-O-benzyl-D-serine is able to inhibit atherosclerotic lesions caused by piperidine, which has been shown to be synthesized from benzyl alcohol and piperidine. The oral administration of this compound can enhance fibroblast cells that are resistant to insulin.
Synthese
N-Boc D-Se (500 mg, 2.43 mmol) dissolved in anhydrous DMF (4 mL) was slowly added to a dispersion of 60% NaH (204 mg, 5.1 mmol) in anhydrous DMF at 0 ° C. Stir the mixture at room temperature for 1 hour and cool to 0 ° C. Subsequently, benzyl bromide (0.29 mL, 2.43 mmol) was added and the mixture was heated to room temperature. After 4 hours of reaction, add saturated NH4Cl (1 mL) to quench the reaction. Finally, the product Boc-D-Ser(Bzl)-OH was obtained through purification.
Boc-D-Ser(Bzl)-OH Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Boc-D-Ser(Bzl)-OH Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 272)Lieferanten
47173-80-8()Verwandte Suche:
- (2R)-2-(tert-butoxycarbonylamino)-3-(phenylmethoxy)propanoic acid
- (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(phenylmethoxy)propanoic acid
- (2R)-2-[(tert-butoxy-oxomethyl)amino]-3-(phenylmethoxy)propanoic acid
- (2R)-3-(benzyloxy)-2-(tert-butoxycarbonylamino)propionic acid
- L-Serine, N-((1,1-dimethylethoxy)carbonyl)-O-(phenylmethyl)-
- Boc-D-Ser(Bzl)-OH, >=98%
- BOC-D-SERINE(BZL)-OH
- BOC-D-SER(BZL)-OH
- BOC-SERINE(BZL)-OH
- BOC-(S)-2-AMINO-3-BENZYLOXYPROPIONIC ACID
- BOC-O-BENZYL-D-SERINE
- BOC-(R)-2-AMINO-3-BENZYLOXYPROPIONIC ACID
- BOC-L-SER(BZL)-OH
- BOC-L-SERINE (BZL)
- BOC-L-SER(BZL)
- O-Benzyl-N-(tert-butoxycarbonyl)-D-serine
- Boc-O-benzyl-D-serine≥ 99.5% (HPLC)
- NALPHA-tert-Butoxycarbonyl-O-benzyl-D-serine
- N-BOC-O-Benzyl-D-serine,98%
- N-t-BOC-O-Benzyl-D-serine
- N-Boc-O-Benzyl-D-ser
- Boc-D-Ser(Bzl)-OH Boc-O-benzyl-D-Serine
- N-Boc-O-benzyl-D-serine
Boc-D-Ser(Bzl)-OH
- T-BUTYLOXYCARBONYL-O-BENZYL-D-SERINE
- T-BUTYLOXYCARBONYL-O-BENZYL-L-SERINE
- TBOC-L-SERINE (BZL)
- N-ALPHA-T-BOC-O-BENZYL-L-SERINE
- N-ALPHA-T-BOC-O-BENZYL-D-SERINE
- N-ALPHA-T-BUTOXYCARBONYL-O-BENZYL-L-SERINE
- N-ALPHA-T-BUTYLOXYCARBONYL-O-BENZYL-D-SERINE
- N-ALPHA-TERT-BOC-O-BENZYL-L-SERINE
- N-ALPHA-TERT-BUTYLOXYCARBONYL-O-BENZYL-D-SERINE
- N-ALPHA-TERT-BUTYLOXYCARBONYL-O-BENZYL-L-SERINE
- N-BOC-O-BENZYL-D-SERINE
- Boc-DL-Ser(Bzl)-OH
- N-TERT-BUTOXYCARBONYL-O-BENZYL-D-SERINE
- N-T-BUTOXYCARBONYL-O-BENZYL-L-SERINE
- (Tert-Butoxy)Carbonyl D-Ser(Bzl)-OH
- (2R)-3-(benzylox
- O-Benzyl-N-Boc-D-serine
- O-Benzyl-N-(tert-butoxycarbonyl)-D-serine >
- D-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-
- BOC-SER(BZL)-OH
- BOC-SER(BZL)
- BOC-O-BENZYL-L-SERINE
- (R)-3-(benzyloxy)-2-((tert-butoxycarbonyl)aMino)propanoic acid
- O-BENZYL-N-(TERT-BUTOXYCARBONYL)-D-SERINE
- BOC-D-SER(BZL)
- (2R)-3-(benzyloxy)-2-{[(tert-butoxy)carbonyl]amino}propanoic acid
- N-[(1,1-Dimethylethoxy)carbonyl]-O-(phenylmethyl)-D-serine
- (s)-(+)-3-Benzyloxy-2-(Boc-amino)-1-propanol
- BOC-D-Ser(OBZL)-OH
- 47173-80-8
- 47473-80-8
- 47173-80-6
- C15H20NO5
- Specialty Synthesis
- Peptide Synthesis
