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ENALAPRILAT DIHYDRATE

ENALAPRILAT DIHYDRATE Struktur
84680-54-6
CAS-Nr.
84680-54-6
Englisch Name:
ENALAPRILAT DIHYDRATE
Synonyma:
MK-422;ENALAPRILATE;as dihydrate;ENALAPRILAT USP;MK-422 Dihydrate;Enalaprilate USP25;Vasotec IV Dihydrate;Enalaprilat (300 mg);ENALAPRILAT DIHYDRATE;Enalaprilat (1235274)
CBNumber:
CB5373019
Summenformel:
C18H26N2O6
Molgewicht:
366.41
MOL-Datei:
84680-54-6.mol

ENALAPRILAT DIHYDRATE Eigenschaften

Schmelzpunkt:
151-159°C
alpha 
[α]D25 -53.0~-56.0゜ (c=1, CH3OH) (Calculated on dehydrous basis)
storage temp. 
2-8°C
L?slichkeit
H2O: soluble14mg/mL at 60°C (warming for 5 minutes)
Aggregatzustand
Solid
Farbe
White to Off-White
CAS Datenbank
84680-54-6(CAS DataBase Reference)
EPA chemische Informationen
L-Proline, N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-, hydrate (1:2) (84680-54-6)

Sicherheit

WGK Germany  3
RTECS-Nr. TW3590600
HS Code  2933995300

ENALAPRILAT DIHYDRATE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Angiotensin-converting enzyme (ACE) converts angiotensin I to angiotensin II, a peptide hormone that impacts vascular smooth muscle tone and renal salt exchange, driving hypertension. Enalaprilat is the active metabolite of enalapril , an ACE inhibitor with roles in the management of hypertension, congestive heart failure, myocardial infarction, and diabetic nephropathies.. Enalaprilat is esterified with ethanol to produce enalapril in order to enable oral activity and subsequently metabolized in vivo to the active form by various esterases. Enalaprilat is reported to inhibit ACE activity with an IC50 value of 5.8 nM in vitro.

Chemische Eigenschaften

White Solid

Definition

ChEBI: The dihydrate form of enalaprilat, an angiotensin-converting enzyme (ACE) inhibitor that is used (often in the form of its prodrug, enalapril) in the treatment of hypertension and heart failure, for reduction of proteinuria and renal disease in patients wi h nephropathies, and for the prevention of stroke, myocardial infarction, and cardiac death in high-risk patients. Unlike enalapril, enalaprilat is not absorbed by mouth but is administered by intravenous injection.

ENALAPRILAT DIHYDRATE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ENALAPRILAT DIHYDRATE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 174)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652
info@fdachem.com China 20284 58
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29880 58
Hubei xin bonus chemical co. LTD
86-13657291602
linda@hubeijusheng.com CHINA 22963 58
Standardpharm Co. Ltd.
86-714-3992388
overseasales1@yongstandards.com United States 14332 58
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873
sales@chemdad.com China 39894 58
TopScience Biochemical
00852-68527855
info@itopbiochem.com China Hong Kong 902 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 22784 58
AFINE CHEMICALS LIMITED
+86-0571-85134551
sales@afinechem.com China 15352 58

84680-54-6()Verwandte Suche:


  • (S)-1-[N-[1-(CARBOXY)-3-PHENYLPROPYL]-L-ALANYL]-L-PROLINE, DIHYDRATE
  • MK-422
  • ENALAPRILAT DIHYDRATE
  • ENALAPRILATE
  • Enalaprilate USP25
  • ENALAPRILAT USP
  • Enalaprilat (300 mg)
  • Enalaprilic Acid Dihydrate
  • MK-422 Dihydrate
  • Vasotec IV Dihydrate
  • Enalapril Maleate IMpurity–C(EP)
  • Enalapril EP IMpurity C
  • L-Proline,1-[N-(1-carboxy-3-phenylpropyl)-L-alanyl]-, dihydrate, (S)- (9CI)
  • N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline, hydrate (1:2)
  • Enalaprilat dihydrate, >=99%
  • as dihydrate
  • Enalaprilat for system suitability CRS
  • Enalaprilat dihydrate CRS
  • ENALAPRILAT DIHYDRATE USP/EP/BP
  • Enalaprilat (1235274)
  • (S)-1-((S)-2-(((S)-1-Carboxy-3-phenylpropyl)amino)propanoyl)pyrrolidine-2-carboxylic acid dihydrate
  • Enalapril EP Impurity C(Hydrate)
  • 84680-54-6
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Inhibitors
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