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RAS INHIBITORY PEPTIDE

RAS INHIBITORY PEPTIDE Struktur
159088-48-9
CAS-Nr.
159088-48-9
Englisch Name:
RAS INHIBITORY PEPTIDE
Synonyma:
VPPPVPPRRR-NH2;RAS INHIBITORY PEPTIDE;Sos SH3 domain inhibitor;Sos SH3 domain inhibitor inhibitor;VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG;HSOS (1149-1158) N10 SH3 BINDING DOMAIN;H-VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-OH;L-Arginine, L-valyl-L-prolyl-L-prolyl-L-prolyl-L-valyl-L-prolyl-L-prolyl-L-arginyl-L-arginyl-
CBNumber:
CB5356014
Summenformel:
C53H91N19O11
Molgewicht:
1170.41
MOL-Datei:
159088-48-9.mol

RAS INHIBITORY PEPTIDE Eigenschaften

Dichte
1.52±0.1 g/cm3(Predicted)
storage temp. 
−20°C
L?slichkeit
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: Miscible; PBS (pH 7.2): 10 mg/ml
Aggregatzustand
A crystalline solid
pka
3.31±0.10(Predicted)

Sicherheit

WGK Germany  3

RAS INHIBITORY PEPTIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to the activation of ERK. Ras inhibitory peptide is a synthetic peptide that contains the sequence PVPPR, which corresponds to a region within human Sos1 that interacts with an SH3 domain of Grb2. It specifically blocks the interaction of the GEF with Grb2, preventing an interaction that is essential for Ras activation by receptor tyrosine kinases, including epidermal growth factor receptor.

RAS INHIBITORY PEPTIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

RAS INHIBITORY PEPTIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 50)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715
 admin@nexconn.com China 10311 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
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Zhejiang Hangyu API Co., Ltd 		+8617531972939
 anna@api-made.com China 2943 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
Changsha MOL Changes Biotechnology Co., Ltd. 		+8619375158599
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GL Biochem (Shanghai) Ltd 21-61263452 13641803416
 ymbetter@glbiochem.com China 9981 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696
 info@hanhongsci.com China 42958 64
Chemsky (shanghai) International Co.,Ltd 021-50135380
shchemsky@sina.com China 15402 60
Chengdu Youngshe Chemical Co., Ltd. +86-17380623303 +86-17380623303
 Caroline@youngshechem.com China 4813 58
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919
Eric@peptidego.com China 6968 58
  • RAS INHIBITORY PEPTIDE
  • VPPPVPPRRR-NH2
  • VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG
  • H-VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-OH
  • HSOS (1149-1158) N10 SH3 BINDING DOMAIN
  • Sos SH3 domain inhibitor
  • L-Arginine, L-valyl-L-prolyl-L-prolyl-L-prolyl-L-valyl-L-prolyl-L-prolyl-L-arginyl-L-arginyl-
  • Sos SH3 domain inhibitor inhibitor
  • 159088-48-9
  • C53H91N19O11
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Reagents
  • G Protein Function
  • G Proteins and Cyclic Nucleotides
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