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Aprepitant Impurity 9

Aprepitant Impurity 9 Struktur
219821-37-1
CAS-Nr.
219821-37-1
Englisch Name:
Aprepitant Impurity 9
Synonyma:
Aprepitant Impurity 9;Aprepitant Impurity 47;Fosaprepitant Impurity U;Aprepitant Open-Ring Methyl Ester Impurity;Aprepitant impurity 22/Aprepitant Open-Ring Methyl Ester Impurity;Methyl 2-(2-((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl) morpholino)-1-iminoethyl)hydrazinecarboxylate;methyl 2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate;2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]hydrazinecarboxylic acid methyl ester;Hydrazinecarboxylic acid, 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]-, methyl ester
CBNumber:
CB53358992
Summenformel:
C24H25F7N4O4
Molgewicht:
566.47
MOL-Datei:
219821-37-1.mol

Aprepitant Impurity 9 Eigenschaften

Dichte
1.43±0.1 g/cm3(Predicted)
L?slichkeit
soluble in Chloroform, Dichloromethane, Methanol
Aggregatzustand
Solid
pka
7.86±0.43(Predicted)
Farbe
Pale-Yellow

Sicherheit

Aprepitant Impurity 9 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

N-(Destriazolonomethyl), N-(Methylcarboxyacetamidohydrazono) Aprepitant is a derivative of Aprepitant (A729800), a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1.

Aprepitant Impurity 9 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

2-Benzylaminoethanol

Downstream Produkte

Aprepitant

Aprepitant Impurity 9 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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219821-37-1()Verwandte Suche:

  • Aprepitant Impurity 9
  • Aprepitant Open-Ring Methyl Ester Impurity
  • 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]hydrazinecarboxylic acid methyl ester
  • Aprepitant impurity 22/Aprepitant Open-Ring Methyl Ester Impurity
  • Aprepitant Impurity 47
  • Methyl 2-(2-((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl) morpholino)-1-iminoethyl)hydrazinecarboxylate
  • Hydrazinecarboxylic acid, 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]-, methyl ester
  • methyl 2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate
  • Fosaprepitant Impurity U
  • 219821-37-1
  • C24H25F7N4O4
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