2-N-HEXYL-4-PENTYNOIC ACID
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- CAS-Nr.
- 96017-59-3
- Englisch Name:
- 2-N-HEXYL-4-PENTYNOIC ACID
- Synonyma:
- Hexyl-4-pentynoic Acid;2-Hexyl-4-pentynoic Acid;2-PROPARGYLOCTANOIC ACID;2-Hexyl-4-pentynoicAcid>2-N-HEXYL-4-PENTYNOIC ACID;2-(2-PROPYNYL)OCTANOIC ACID;Hexyl-4-pentynoic acid (HPA);R-2-(2-propynyl)octanoic acid;2-(2-Propyn-1-yl)octanoic Acid;2-(Prop-2-yn-1-yl)octanoic acid
- CBNumber:
- CB5317246
- Summenformel:
- C11H18O2
- Molgewicht:
- 182.26
- MOL-Datei:
- 96017-59-3.mol
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2-N-HEXYL-4-PENTYNOIC ACID Eigenschaften
- Siedepunkt:
- 287.1±23.0 °C(Predicted)
- Dichte
- 0.94
- Brechungsindex
- 1.4450-1.4510
- storage temp.
- Inert atmosphere,Room Temperature
- L?slichkeit
- Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
- Aggregatzustand
- oil
- pka
- 4.24±0.21(Predicted)
- Farbe
- Colorless
- Stabilit?t:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
2-N-HEXYL-4-PENTYNOIC ACID Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
2-
hexyl-
4-
Pentynoic acid is a derivative of valproic acid , an inhibitor of histone deacetylases (HDACs). It inhibits HDAC activity more potently (IC
50 = 13 μM) than valproic acid (IC
50 = 398 μM). 2-
hexyl-
4-
Pentynoic acid induces histone hyperacetylation in cerebellar granule cells significantly at 5 μM. It also induces the expression of heat shock proteins Hsp70-
1a and Hsp70-
1b and protects cerebellar granule cells from glutamate-
induced excitotoxicity when used at a concentration of 50 μM.
2-N-HEXYL-4-PENTYNOIC ACID Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-N-HEXYL-4-PENTYNOIC ACID Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 51)Lieferanten
96017-59-3()Verwandte Suche:
- 2-(2-PROPYNYL)OCTANOIC ACID
- 2-N-HEXYL-4-PENTYNOIC ACID
- 2-PROPARGYLOCTANOIC ACID
- 2-Hexyl-4-pentynoic Acid
- 2-Propargyloctanoic Acid
2-(2-Propynyl)octanoic Acid
- 2-Hexyl-4-pentynoicAcid>
- 2-(Prop-2-yn-1-yl)octanoic acid
- Hexyl-4-pentynoic acid (HPA)
- R-2-(2-propynyl)octanoic acid
- Hexyl-4-pentynoic Acid
- HDAC inhibitor,Heat shock proteins,HSP70,Excitotoxicity,Histone deacetylases,inhibit,HDAC,Neuroprotection,2hexyl4Pentynoic Acid,2 hexyl 4 Pentynoic Acid,Inhibitor,Glutamate,HSP,Valproic acid
- Octanoic acid, 2-(2-propyn-1-yl)-
- 2-(2-Propyn-1-yl)octanoic Acid
- 96017-59-3
- Acetylenic Carboxylic Acids & Their Derivatives
- Acetylenes
- Acetylenic Carboxylic Acids & Their Derivatives
- Acetylenes