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2-Desoxy-D-ribose

2-Deoxy-D-ribose Struktur
533-67-5
CAS-Nr.
533-67-5
Bezeichnung:
2-Desoxy-D-ribose
Englisch Name:
2-Deoxy-D-ribose
Synonyma:
Deoxyribose;D-2-DEOXYRIBOSE;THYMINOSE;2-DEOXYRIBOSE;D-erythro-Pentose, 2-deoxy-;(3S,4R)-3,4,5-trihydroxypentanal;desoxyribose;D-deoxyribose;(2R,4S,5R)-5-(hydroxyMethyl)tetrahy-drofuran-2,4-diol;ribodesose
CBNumber:
CB5315585
Summenformel:
C5H10O4
Molgewicht:
134.13
MOL-Datei:
533-67-5.mol

2-Desoxy-D-ribose Eigenschaften

Schmelzpunkt:
89-90 °C(lit.)
Siedepunkt:
167.23°C (rough estimate)
alpha 
-57 º (c=1, H2O, 24hr)
Dichte
1.0590 (rough estimate)
Brechungsindex
-56 ° (C=1, H2O)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
L?slichkeit
DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated)
Aggregatzustand
Crystalline Powder
pka
12.61(at 25℃)
Farbe
White to slightly yellow
Optische Aktivit?t
[α]22/D 59°, c = 1 in H2O
Wasserl?slichkeit
soluble
Sensitive 
Hygroscopic
Merck 
14,2908
BRN 
1721978
Stabilit?t:
Hygroscopic
InChIKey
ASJSAQIRZKANQN-CRCLSJGQSA-N
CAS Datenbank
533-67-5(CAS DataBase Reference)
NIST chemische Informationen
D-Erythro-pentose, 2-deoxy-(533-67-5)
EPA chemische Informationen
D-erythro-Pentose, 2-deoxy- (533-67-5)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn,Xi
R-S?tze: 20/21/22-36/37/38
S-S?tze: 24/25-37/39-36-26
WGK Germany  3
RTECS-Nr. SB7230000
3-10
TSCA  Yes
HS Code  29400000
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H332 Gesundheitssch?dlich bei Einatmen. Akute Toxizit?t inhalativ Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P261, P271, P304+P340, P312
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

2-Desoxy-D-ribose Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S24/25:Berührung mit den Augen und der Haut vermeiden.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Beschreibung

2-deoxy-D-Ribose is a reducing sugar formed as a degradation product during metabolism of thymidine by thymidine phosphorylase. It increases levels of reactive oxygen species (ROS) in HL-60 human leukemia cells when used at a concentration of 15 mM. 2-deoxy-D-Ribose (10 μM) induces tubulogenesis and migration of bovine aortic endothelial (BAE) cells. Topical administration of 2-deoxy-D-ribose increases blood vessel formation and accelerates wound healing in a rat full-thickness cutaneous wound model.
2-Deoxy-D-ribose ball and stick model

Verwenden

2-Deoxy-D-ribose (2dDR) can be used to prepare multifunctional wound dressings capable of inducing rapid angiogenesis with antimicrobial activity, such as 2dDR-SA hydrogel. The gel can be used to stimulate wound healing and treat superficial skin wounds, including chronic wound care. In addition, 2dDR gel has the potential to treat androgenetic alopecia and other causes of alopecia areata.

Definition

ChEBI: 2-deoxy-D-ribose is a deoxypentose that is D-ribose in which the hydroxy group at position C-2 is replaced by hydrogen. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is functionally related to a D-ribose.

Biologische Aktivit?t

2-Deoxy-D-ribose (2dDR) is a D-isomer of a deoxypentose monosaccharide in which a hydrogen atom is present with a hydroxyl group at the C-2 position in place of the hydroxyl group. 2dDR is known to enhance tubulogenesis, prevent hypoxia-induced apoptosis, and boost VEGF and IL-8 production of ECs in vitro, consistent with the stimulatory effects of 2dDR on cell proliferation and migration. 2dDR also stimulated angiogenesis, proliferation of endothelial cells, and accelerated wound healing in rat models. Additionally, 2dDR can be loaded into several biomaterials for prolonged release over several days to promote the growth of neonatal blood vessels[1].

2-Desoxy-D-ribose Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


2-Desoxy-D-ribose Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 721)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hu Bei Jiutian Bio-medical Technology CO.,Ltd
027-88013699 17354350817
Ryan@jiutian-bio.com China 6001 58
Beijing Ribio Biotech Co.,Ltd
010-62664360 +8613328773880
wucy@ribio.com.cn China 117 58
Wuhan Fortuna Chemical Co.,Ltd
+8618007136271
hk@fortunachem.com China 5999 58
Watson Biotechnology Co.,Ltd
+86-18186686046 +86-18186686046
sales01@watsonbiotech.cn China 5859 58
INNOBIO PHARM CO.,LTD
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cindyyb@126.com China 269 58
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+86-0086-0373-3088722 +8618637352520
info@aurora-biotech.com China 94 58
Hebei Weibang Biotechnology Co., Ltd
+8615531157085
abby@weibangbio.com China 8803 58
Hebei Mujin Biotechnology Co.,Ltd
+86 13288715578 +8613288715578
sales@hbmojin.com China 12825 58
Hebei Yanxi Chemical Co., Ltd.
+8617531153977
allison@yan-xi.com China 5855 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325
sales1@chuanghaibio.com China 5881 58

533-67-5(2-Desoxy-D-ribose)Verwandte Suche:


  • D-.alpha.-Ribodesose
  • D-Ribose, 2-deoxy-
  • 2-deoxy-d-erythro-pentos
  • 2-Deoxypentose
  • 2-Desoxy ribosoe
  • D-(-)-2-DEOXYRIBOSE
  • D-2-DESOXYRIBOSE
  • 2-Deoxy-beta-D-erythro-pentose
  • Deoxy-D-Ribose
  • 2-DEOXY-D-RIBOSE CELL CULTURE TESTED
  • 2-Deoxy-D-Ribose98.0%Min
  • 2-Deoxy-D-ribose,99%
  • 2-DEOXY-D-RIBOSE (D-REYTHRO-2-DEOXYPENTOSE)
  • 2-DEOXY-D-RIBOSE,CRYSTALLINE
  • 3,4,5-trihydroxypentanal
  • ribodesose
  • 2-DEOXY-D-RIBOSE BR
  • D-erythro-Pentose, 2-deoxy- 533-67-5
  • 2-Deoxy-D-riboside
  • 2-Doxy-D-Ribose
  • 2-DEOXY-D-RIBOSE extrapure
  • 2-Deoxy-D-arabinose, 2-Deoxy-D-erythropentose, Thyminose
  • Ribose, 2-deoxy-, D-
  • 2-DESOXY-D-RIBOSE
  • 2-DEOXY-D-RIBOSE
  • 2-DEOXY-D-ARABINOSE
  • 2-DEOXY-D-ERYTHRO-PENTOSE
  • D-ERYTHRO-2-DEOXYPENTOSE
  • DEOXY-D-RIBOSE,2-
  • TETRAHYDRO-2H-PYRAN-2,4,5-TRIOL
  • .alpha.-Deoxy-D-ribose
  • (2S,4S,5R)-Oxane-2,4,5-triol
  • 2-Deoxy-D-riboside >99%
  • 2-Deoxy-D-ribose 97%
  • Cladribine Impurity E
  • NAPTHALENE NEAT
  • 2-Deoxy-D-ribose (Zidovudine)
  • 2-Deoxy-D-arabinose, low endotoxin ≤10 EU/mg
  • 2-Deoxy-D-erythro-pentose, low endotoxin ≤10 EU/mg
  • 2-Deoxy-D-ribose, low endotoxin ≤10 EU/mgCell culture grade, ≥ 99% (HPLC)
  • Cladribine Impurity 5(Cladribine EP Impurity E)
  • (2S,4S,5R)-5-(hydroxymethyl)oxolane-2,4-diol
  • Cladribine EP Impurity E
  • 2DR(2-Deoxy-D-ribose)
  • 2-Deoxy-D-ribose >
  • 2'-Deoxy-D-RMbose,≥98%
  • (4S,5R)-Oxane-2,4,5-triol
  • 2-Deoxy-D-ribose USP/EP/BP
  • dextro-2-deoxyribose
  • 2-DEOXY-D-RIBOSE D2
  • 2-Deoxy-D-RiboseQ: What is 2-Deoxy-D-Ribose Q: What is the CAS Number of 2-Deoxy-D-Ribose Q: What is the storage condition of 2-Deoxy-D-Ribose Q: What are the applications of 2-Deoxy-D-Ribose
  • Deoxyribose
  • D-2-DEOXYRIBOSE
  • D-erythro-Pentose, 2-deoxy-
  • desoxyribose
  • 2-DEOXYRIBOSE
  • THYMINOSE
  • D-deoxyribose
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