17β-hydroxy Wortmannin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

17β-hydroxy Wortmannin is an analog of wortmannin. It irreversibly binds phosphoinositide 3-kinase (PI3K) and potently blocks fMLP-stimulated respiratory burst in neutrophils (IC₅₀ = 5 nM). 17β-hydroxy Wortmannin inhibits recombinant PI3K and mTOR (IC₅₀ = 2.7 and 193 nM, respectively) and prevents the growth of LNCap prostate cancer cells (IC₅₀ = 1.46 μM). The 17-hydroxyl group has been used to further modify this compound, e.g., by pegylation and conjugation with rapamycin.

17β-hydroxy Wortmannin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

17β-hydroxy Wortmannin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
BOC Sciences	16314854226	info@bocsci.com	United States	9923	65
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6777	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8140	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11974	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	19704	58
Hubei Danding Pharmaceutical Technology Co., Ltd	18917019315 18917019315	18917019315@163.cn	China	9162	58

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• 17β-hydroxy Wortmannin Exclusive
• XLJORQYAOTYVQS-OGCOKEDGSA-N
• 17.beta.-hydroxy Wortmannin
• PI 3-K Inhibitor XI, HWT - CAS 58053-83-1 - Calbiochem
• 3H-Furo[4,3,2-de]indeno[4,5-h]-2-benzopyran-3,6(1H)-dione, 11-(acetyloxy)-6b,7,8,9,9a,10,11,11b-octahydro-9-hydroxy-1-(methoxymethyl)-9a,11b-dimethyl-, (1S,6bR,9S,9aS,11R,11bR)-
• 17β-hydroxy Wortmannin
• 17β-hydroxy Wortmannin Exclusive
• 58053-83-1