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R-268712

R-268712 Struktur
879487-87-3
CAS-Nr.
879487-87-3
Englisch Name:
R-268712
Synonyma:
2025;R-268712;CID 11703284;R 268712;R268712;R-268712, 10 mM in DMSO;4-[2-Fluoro-5-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]-1H-pyrazole-1-ethanol;1H-Pyrazole-1-ethanol, 4-[2-fluoro-5-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]-;2-(4-(2-fluoro-5-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)phenyl)-1H-pyrazol-1-yl)ethanol;2-(4-(2-Fluoro-5-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)phenyl)-1H-pyrazol-1-yl)ethan-1-ol;renal fibrosis,Thy1 nephritis,Transforming growth factor beta receptors,glomerulonephritis,Transforming growth factor beta,ALK tyrosine kinase receptor,HFL-1,R 268712,glomerulosclerosis,CD246,Inhibitor,Cluster of differentiation 246,UUO,Anaplastic lymphoma kinase (ALK),R268712,inhibit,TGF-β,TGF-beta/Smad,CKD,R-268712,TGF-β Receptor,Anaplastic lymphoma kinase
CBNumber:
CB53126704
Summenformel:
C20H18FN5O
Molgewicht:
363.39
MOL-Datei:
879487-87-3.mol

R-268712 Eigenschaften

Siedepunkt:
576.8±50.0 °C(Predicted)
Dichte
1.34±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
L?slichkeit
DMSO : 125 mg/mL (343.98 mM)
pka
10.96±0.50(Predicted)
Aggregatzustand
Solid
Farbe
White to light yellow

Sicherheit

R-268712 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

R 268712 is an orally active transforming growth factor-β type I receptor inhibitor, which prevents glomerular sclerosis in a Thy1 nephritis model.

R-268712 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

R-268712 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 35)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32965 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
LEAPCHEM CO., LTD. 		+86-852-30606658
market18@leapchem.com China 43340 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185
 sales-cpd@caerulumpharma.com China 3466 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057
 3003855609@qq.com China 7787 56
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266
 China 4573 55
Musechem +1-800-259-7612
info@musechem.com United States 4660 60
Shenzhen Regent Biochemical Technology Co., Ltd. 0755-0755-85201366 18938635012
 sales@regentsciences.com China 9520 58
Henan Weituxi Chemical Technology Co., Ltd. 0371-63284658 18135795563
 2885349392@qq.com China 9976 58
  • R-268712
  • 1H-Pyrazole-1-ethanol, 4-[2-fluoro-5-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]-
  • 4-[2-Fluoro-5-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]-1H-pyrazole-1-ethanol
  • R 268712;R268712
  • 2025
  • 2-(4-(2-Fluoro-5-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)phenyl)-1H-pyrazol-1-yl)ethan-1-ol
  • renal fibrosis,Thy1 nephritis,Transforming growth factor beta receptors,glomerulonephritis,Transforming growth factor beta,ALK tyrosine kinase receptor,HFL-1,R 268712,glomerulosclerosis,CD246,Inhibitor,Cluster of differentiation 246,UUO,Anaplastic lymphoma kinase (ALK),R268712,inhibit,TGF-β,TGF-beta/Smad,CKD,R-268712,TGF-β Receptor,Anaplastic lymphoma kinase
  • 2-(4-(2-fluoro-5-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)phenyl)-1H-pyrazol-1-yl)ethanol
  • CID 11703284
  • R-268712, 10 mM in DMSO
  • 879487-87-3
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