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SR1824

SR1824 Struktur
1338259-06-5
CAS-Nr.
1338259-06-5
Englisch Name:
SR1824
Synonyma:
SR1824;HBMXDCXJXYASGW-NRFANRHFSA-N;[1,1'-Biphenyl]-2-carboxylic acid, 4'-[[5-[[[(1S)-1-(4-bromophenyl)ethyl]amino]carbonyl]-2,3-dimethyl-1H-indol-1-yl]methyl]-
CBNumber:
CB53039567
Summenformel:
C33H29BrN2O3
Molgewicht:
581.5
MOL-Datei:
1338259-06-5.mol

SR1824 Eigenschaften

Siedepunkt:
809.7±65.0 °C(Predicted)
Dichte
1.32±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
Aggregatzustand
crystalline solid
pka
3.87±0.36(Predicted)

Sicherheit

SR1824 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Peroxisome proliferator-activated receptor γ (PPARγ) is activated by the anti-diabetes drugs known as thiazolidinediones, including rosiglitazone and pioglitazone . Phosphorylation of PPARγ by cyclin-dependent kinase 5 (Cdk5) causes dysregulation of genes whose expression is altered in obesity, including adiponectin. SR 1824 is a non-agonist PPARγ ligand (Ki = 10 nM) which blocks Cdk5-mediated phosphorylation. It does not inhibit activation of PPARγ by rosiglitazone .

Verwenden

SR 1824 is a non-agonist Peroxisome proliferator-activated receptor γ (PPARγ) ligand.

SR1824 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


SR1824 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 27)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11218 58
Energy Chemical 021-58432009 400-005-6266
marketing1@energy-chemical.com China 44807 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912
order@med-bio.cn China 8140 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
customer_service@efebio.com China 11974 58
United States Biological --
sales@advtechind.com United States 6075 58
ApexBio Technology --
sales@apexbt.com United States 6251 58

  • SR1824
  • HBMXDCXJXYASGW-NRFANRHFSA-N
  • [1,1'-Biphenyl]-2-carboxylic acid, 4'-[[5-[[[(1S)-1-(4-bromophenyl)ethyl]amino]carbonyl]-2,3-dimethyl-1H-indol-1-yl]methyl]-
  • 1338259-06-5
  • C33H29BrN2O3
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