Oritavancin Diphosphate
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- CAS-Nr.
- 192564-14-0
- Englisch Name:
- Oritavancin Diphosphate
- Synonyma:
- OC/ QTH05;LY 333328 diphosphate;Oritavancin (phosphate);Oritavancin Diphosphate;LY 333328;ORITAVANCIN (PHOSPHATE);Oritavancin diphosphate (LY333328);oritavancin,LY333328 diphosphate salt;(4''R)-22-o-(3-Amino-2,3,6-trideoxy-3-C-methyl-α-L-arabino-hexopyranosyl)-N3''-[(4'-chloro[1,1'-biphenyl]-4-yl)methyl]-vancomycin phosphate (1:2);(4''R)-22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-α-L-arabino-hexopyranosyl)-N3''-[(4'-chloro[1,1'-biphenyl]-4-yl)methyl]-Vancomycin phosphate (1:2);Vancomycin, 22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-α-L-arabino-hexopyranosyl)-N3''-[(4'-chloro[1,1'-biphenyl]-4-yl)methyl]-, (4''R)-, phosphate (1:2)
- CBNumber:
- CB52611438
- Summenformel:
- C86H103Cl3N10O34P2
- Molgewicht:
- 1989.091142
- MOL-Datei:
- 192564-14-0.mol
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Oritavancin Diphosphate Eigenschaften
- Schmelzpunkt:
- >229°C (dec.)
- storage temp.
- -20°C
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- powder
- Farbe
- white to beige
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H317 |
Kann allergische Hautreaktionen verursachen. |
Sensibilisierung der Haut |
Kategorie 1A |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P272 |
Kontaminierte Arbeitskleidung nicht au?erhalb des Arbeitsplatzes tragen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P333+P313 |
Bei Hautreizung oder -ausschlag: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
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Oritavancin Diphosphate Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Oritavancin diphosphate is a glycopeptide analog related to the
vancomycin class of antibiotics that inhibits the transpeptidase
and transglycosylation steps of bacterial peptidoglycan cell-wall
synthesis. The compound was discovered and initially developed
by Eli Lilly and Co. The development of the compound was
sold to Intermune and then to Targanta which was acquired by
The Medicines Company who achieved approval of the drug by
the US FDA for the treatment of acute bacterial skin and skin-structure
infections caused by gram-positive bacteria. It is also
approved for the treatment of methicillin-resistant Staphylococcus
aureus (MRSA) infections.
Verwenden
Antibacterial (peptidoglycan synthesis inhibitor).
Definition
ChEBI: A phosphate salt obtained by combining oritavancin with two molar equivalents of phosphoric acid. Used for the treatment of acute bacterial skin and skin structure infections caused or suspected to be caused by susceptible isolates of designated Gram-posit
ve microorganisms.
Oritavancin Diphosphate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Oritavancin Diphosphate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 111)Lieferanten
192564-14-0()Verwandte Suche:
- Oritavancin Diphosphate
- LY 333328 diphosphate
- Oritavancin (phosphate)
- oritavancin,LY333328 diphosphate salt
- LY 333328;ORITAVANCIN (PHOSPHATE)
- OC/ QTH05
- Oritavancin diphosphate (LY333328)
- Vancomycin, 22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-α-L-arabino-hexopyranosyl)-N3''-[(4'-chloro[1,1'-biphenyl]-4-yl)methyl]-, (4''R)-, phosphate (1:2)
- (4''R)-22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-α-L-arabino-hexopyranosyl)-N3''-[(4'-chloro[1,1'-biphenyl]-4-yl)methyl]-Vancomycin phosphate (1:2)
- (4''R)-22-o-(3-Amino-2,3,6-trideoxy-3-C-methyl-α-L-arabino-hexopyranosyl)-N3''-[(4'-chloro[1,1'-biphenyl]-4-yl)methyl]-vancomycin phosphate (1:2)
- 192564-14-0
- C86H97Cl3N10O262H3PO4
- C86H103Cl3N10O34P2
- Inhibitors
