Calicheamicin Chemische Eigenschaften,Einsatz,Produktion Methoden
Definition
Calicheamicins (CLM) is an endiyne antitumor antibiotic isolated from the fermentation broth of the rare Micromonospora actinomycetes.
Application
Calicheamicin is extremely toxic to all cells and, in 2000, a CD33 antigen-targeted immunoconjugate N-acetyl dimethyl hydrazide calicheamicin was developed and marketed as targeted therapy against the non-solid tumor cancer acute myeloid leukemia (AML).
Calicheamicin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte