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Bepheniumhydroxynaphthoat

BEPHENIUM HYDROXYNAPHTHOATE Struktur
3818-50-6
CAS-Nr.
3818-50-6
Bezeichnung:
Bepheniumhydroxynaphthoat
Englisch Name:
BEPHENIUM HYDROXYNAPHTHOATE
Synonyma:
Bephenium;BEPHENIUM HYDROXYNAPTHOATE;BEPHENIUM HYDROXYNAPHTHOATE;3-hydroxynaphthalene-2-carboxylate;Bephenium Hydroxynaphthoate (500 mg);BEPHENIUM HYDROXYNAPHTHOATE USP/EP/BP;Bephenium Hydroxynaphthoate (1065006);dimethyl-[2-(phenoxy)ethyl]-(phenylmethyl)azanium;Bephenium (hydroxynaphthoate),Inhibitor,Parasite,inhibit;BENZYLDIMETHYL[2-PHENOXYETHYL]-AMMONIUM 3-HYDROXYNAPHTHOATE
CBNumber:
CB5206454
Summenformel:
C28H29NO4
Molgewicht:
443.53
MOL-Datei:
3818-50-6.mol

Bepheniumhydroxynaphthoat Eigenschaften

Schmelzpunkt:
170-171°
storage temp. 
Store at -20°C
L?slichkeit
≥ 20.85mg/mL in DMSO
Aggregatzustand
Solid
Farbe
White to off-white

Sicherheit

WGK Germany  3

Bepheniumhydroxynaphthoat Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

antibacterial, antilepretic, antituberculosis

Indications

This drug exhibits antihelmintic action by acting as a cholinergic agonist, causing paralysis of the parasite musculature. This facilitates its removal from the intestines. It is used for treating ascariasis, ankylostomiasis, enterobiasis, trichostrongyliasis, and tricocefalosis. A single dose of bephenium heals from 80 to 100% of patients infected with A. duodenale. It is less effective with respect to N. americanus. Synonyms of this drug are aclopar and others.

Synthese

Bephenium, 3-hydroxy-2-naphthoat benzyldimethyl(2-phenoxyethyl) ammonia (38.1.37), is made by reacting the sodium salt of 3-hydroxy-2-naphthoic acid with benzyldimethyl(2-phenoxyethyl)ammonia chloride (38.1.36). This is in turn made from benzyl chloride and N-(2-phenoxyethyl)dimethylamine (38.1.35), which is synthesized by reacting sodium phenolate with 2-dimethylaminoethylchloride.

Synthesis_3818-50-6

Bepheniumhydroxynaphthoat Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Bepheniumhydroxynaphthoat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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3818-50-6(Bepheniumhydroxynaphthoat)Verwandte Suche:


  • BENZYLDIMETHYL[2-PHENOXYETHYL]-AMMONIUM 3-HYDROXYNAPHTHOATE
  • BEPHENIUM HYDROXYNAPHTHOATE
  • benzyldimethyl-2-phenoxyethylammonium 3-hydroxy-2-naphthoate
  • 3-hydroxynaphthalene-2-carboxylate
  • dimethyl-[2-(phenoxy)ethyl]-(phenylmethyl)azanium
  • Bephenium Hydroxynaphthoate (500 mg)
  • BEPHENIUM HYDROXYNAPTHOATE
  • BEPHENIUM HYDROXYNAPHTHOATE USP/EP/BP
  • N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate
  • Bephenium Hydroxynaphthoate (1065006)
  • Bephenium
  • Bephenium (hydroxynaphthoate),Inhibitor,Parasite,inhibit
  • 3818-50-6
  • C17H22NOC11H7O3
  • Analytical Standards
  • Analytical Chromatography Product Catalog
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