HUMAN M-CSF
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- CAS-Nr.
- 81627-83-0
- Englisch Name:
- HUMAN M-CSF
- Synonyma:
- csf-1;M-CSF;MGI-IM;mCSF-1;mM-CSF;RHM-CSF;MGC31930;M-CSF rat;Lanimostim;HUMAN CSF-1
- CBNumber:
- CB5201242
- Summenformel:
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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HUMAN M-CSF Eigenschaften
- storage temp.
- -20°C
- Aggregatzustand
- lyophilized powder
- Farbe
- white to off-white
- Biologische Quelle
- rat
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P271 |
Nur im Freien oder in gut belüfteten R?umen verwenden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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HUMAN M-CSF Chemische Eigenschaften,Einsatz,Produktion Methoden
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Verwenden
Antineoplastic; anti-infective
growth factor that acts on both progenitor and mature
cells of the macrophage line.
Allgemeine Beschreibung
M-CSF (macrophage colony-stimulating factor) is a potent hematopoietic factor produced by a variety of cells including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. The protein works through its receptor CSF1R (colony stimulating factor 1 receptor). The human is reactive in murine systems, but the murine molecule exhibits no activity on human cells. Recombinant murine M-CSF is a 36.4kDa homodimeric protein containing two 156 amino acid polypeptide subunits.
Biochem/physiol Actions
M-CSF (macrophage colony-stimulating factor) is a key regulator of cellular proliferation, differentiation, and survival of blood monocytes, tissue macrophages and their progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness, and male and female fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation. M-CSF also works as a pleiotropic growth factor and plays a crucial role in reproduction and organogenesis. Absence of it can result in reduced growth, neurological and reproductive problems, developmental defects in the mammary gland, bone and pancreas. M-CSF is also involved in the pathogenesis of cancer.
HUMAN M-CSF Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
HUMAN M-CSF Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 115)Lieferanten
81627-83-0()Verwandte Suche:
(Pentan-2,4-dionato-O,O')silber
Kupfer(II)-4-oxopent-2-en-2-olat
Tris(2,2,6,6-tetramethylheptan-3,5-dionato-O,O')europium
1,1,3,3-Tetramethylbutylisocyanat
Methylisocyanacetat
Aluminiumtris(2,4-pentandionato-O,O')
2-Methylpropylisocyanid
Ethylisocyanacetat
(p-Toluolsulfonyl)methylisocyanid
Dichloro(ethylendiamin)platin
N-Butylisocyanid
Benzylisocyanid
Phenylselenol
(Ethylenbis(nitrilomethylidyn)-2,2'-diphenolato)cobalt(II)
Tris(pentan-2,4-dionato)eisen(II)
Tris(2,2,6,6-tetramethylheptan-3,5-dionato-O,O')dysprosium
- colony-stimulatingfactor1
- csf-1
- MGI-IM
- Monoclonal Anti-CSF1 antibody produced in mouse
- MGC31930
- ANTI-M-CSF (CENTER) antibody produced in rabbit
- Lanimostim
- Macrophage colony-stimulating factor 1
- Processed macrophage colony-stimulating factor 1
- MACROPHAGE COLONY STIMULATOR FACTOR (M-CSF) HUMAN
- MACROPHAGE COLONY STIMULATING FACTOR
- MACROPHAGE COLONY STIMULATING FACTOR, HUMAN
- MACROPHAGE COLONY-STIMULATING FACTOR, HUMAN, RECOMBINANT
- M-CSF
- M-CSF, HUMAN
- HUMAN MACROPHAGE COLONY STIMULATING FACTOR
- HUMAN MGI-IM
- HUMAN CSF-1
- Macrophage Colony-StimulatingFactor, Human, Recomb.
- MACROPHAGE-COLONY STIMULATING FACTOR, HU MAN RECOMBINANT EXPRESSED IN E. COLI
- macrophagehumanrecombinantexpressedinyeast95+%
- macrophage colony-stimulating factor from mouse
- FOR USE IN THE MANUFACTURE OF MEDICAMENTS OF HS NO. 3002
- mCSF-1
- mM-CSF
- M-CSF from rat
- M-CSF rat
- M-CSF from mouse
- cytokines,macrophagecolony-stimulatingfactor
- monocytecolony-stimulatingfactor
- RHM-CSF
- RECOMBINANT HUMAN M-CSF
- NATURAL HUMAN CSF-1
- NATURAL HUMAN MACROPHAGE-COLONY STIMULATING FACTOR
- NATURAL HUMAN M-CSF
- HUMAN M-CSF
- Recombinant Rat M-Csf/Csf1 Protein, No Tag
- Recombinant Human M-CSF, HUMAN M-CSF
- Macrophage Colony-Stimulating Factor, Human, Recombinant, E. coli
- Recombinant Human M-CSF/CSF1 Protein, His Tag
- Recombinant Mouse M-Csf/Csf1 Protein, No Tag
- Macrophage Colony-Stimulating Factor, Human, Recombinant, E. coli
- 81627-83-0
- BioChemical
- Cell Biology
- Cell Signaling and Neuroscience
- Cytokines and Growth Factors
- Cytokines, Growth Factors and Hormones
- Hematopoietic Cytokines
