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LY 367385

LY 367385 Struktur
198419-91-9
CAS-Nr.
198419-91-9
Englisch Name:
LY 367385
Synonyma:
LY 367385;LY367385,LY-367385;LY-367385 hydrochloride;SGIKDIUCJAUSRD-QMMMGPOBSA-N;(S)-4-[aMino(carboxy)Methyl]-3-Methylbenzoic acid;4-[(R)-amino(carboxy)methyl]-3-methylbenzoic acid;4-[(S)-amino(carboxy)methyl]-3-methylbenzoic acid;(S)-(+)-α-Amino-4-carboxy-2-methylbenzeneaceticacid;(S)-(+)-a-amino-4-carboxy-2-methylbenzeneacetic acid;(S)-(+)-α-Amino-4-carboxy-2-methylbenzeneacetic acid
CBNumber:
CB5200038
Summenformel:
C10H11NO4
Molgewicht:
209.2
MOL-Datei:
198419-91-9.mol

LY 367385 Eigenschaften

storage temp. 
Desiccate at RT
L?slichkeit
H2O: >10mg/mL
Aggregatzustand
powder
Farbe
white to off-white

Sicherheit

WGK Germany  3

LY 367385 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

LY 367385 is a selective mGlu1a receptor antagonist used to treat inflammatory diseases (ie. multiple sclerosis) and neurodegenerative diseases (ie. Alzheimer’s) (1,2).

Biologische Aktivit?t

A selective mGlu 1a receptor antagonist, with an IC 50 value of 8.8 μ M for blockade of quisqualate-induced phosphoinositide hydrolysis vs. > 100 μ M for mGlu 5a , and negligible action on group II and III receptors. Also available as part of the Group I mGlu Receptor Tocriset™ .

Biochem/physiol Actions

LY-367385 hydrochloride has an ability to inhibit induction of long-term potentiation (LTP).

LY 367385 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


LY 367385 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 49)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525
masar@topule.com China 8467 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
3bsc@sina.com China 15839 69
Ascent Scientific 4401179829988
customerservice@ascentscientific.co.uk United Kingdom 279 60
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51456 80
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
BOC Sciences --
info@bocsci.com USA 0 65
DC Chemicals 021-58447131 13564518121
sales@dcchemicals.com China 9409 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912
order@med-bio.cn China 8140 58

198419-91-9()Verwandte Suche:


  • (S)-(+)-ALPHA-AMINO-4-CARBOXY-2-METHYLBENZENEACETIC ACID
  • LY 367385
  • (S)-(+)-α-Amino-4-carboxy-2-methylbenzeneaceticacid
  • (S)-4-[aMino(carboxy)Methyl]-3-Methylbenzoic acid
  • (S)-(+)-a-amino-4-carboxy-2-methylbenzeneacetic acid
  • LY-367385 hydrochloride
  • (R)-(+)-alpha-Amino-4-carboxy-2-methylbenzeneacetic acid
  • LY-367385;(R)-(+)-ALPHA-AMINO-4-CARBOXY-2-METHYLBENZENEACETIC ACID
  • (S)-(+)-α-Amino-4-carboxy-2-methylbenzeneacetic acid
  • Benzeneacetic acid, α-amino-4-carboxy-2-methyl-, (αS)-
  • SGIKDIUCJAUSRD-QMMMGPOBSA-N
  • LY367385,LY-367385
  • Benzeneacetic acid, α-amino-4-carboxy-2-methyl-, (αS)-
  • 4-[(R)-amino(carboxy)methyl]-3-methylbenzoic acid
  • 4-[(S)-amino(carboxy)methyl]-3-methylbenzoic acid
  • 198419-91-9
  • Glutamate
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