Methyl 2-bromo-4-fluorobenzoate
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- CAS-Nr.
- 653-92-9
- Englisch Name:
- Methyl 2-bromo-4-fluorobenzoate
- Synonyma:
- RARECHEM AL BF 1088;Bromo-4-fluorobenzoate;2-bromo-4-fluorobenzoate;METHYL 2-BROMO-4-FLUOROBENZOATE;Methyl 4-fluoro-2-bromobenzoate;Methyl2-bromo-4-fluorobenzoate98%;2-bromo-4-fluoro-3-methylbenzoate;Methyl 2-bromo-4-fluorobenzoate 98%;5-fluoro-2-(methoxycarbonyl)bromobenzene;2-Bromo-4-fluorolbenzoicacid methyl ester
- CBNumber:
- CB5198865
- Summenformel:
- C8H6BrFO2
- Molgewicht:
- 233.03
- MOL-Datei:
- 653-92-9.mol
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Methyl 2-bromo-4-fluorobenzoate Eigenschaften
- Siedepunkt:
- 75-78/1mm
- Dichte
- 1.577
- Flammpunkt:
- 100℃
- storage temp.
- Sealed in dry,Room Temperature
- InChI
- InChI=1S/C8H6BrFO2/c1-12-8(11)6-3-2-5(10)4-7(6)9/h2-4H,1H3
- InChIKey
- JENBPOJAZCPSEW-UHFFFAOYSA-N
- SMILES
- C(OC)(=O)C1=CC=C(F)C=C1Br
Methyl 2-bromo-4-fluorobenzoate Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
off-white powder
Synthese
DBU (1.7 equiv, 1.16 mL, 7.76 mmol) was added to a solution of 2-bromo-4-fluorobenzoicacid (1.0equiv, 1.0 g, 4.57 mmol) and iodomethane (2.0 equiv, 0.57 mL, 9.14 mmol) in CH3CN(11 mL) at 23 °C. After stirring for 48 h, the reaction was quenched with H2O(10 mL) and extracted with Et2O (2 x 10 mL). The combined organic extracts were washed with water (20 mL) and brine (20 mL), dried over Na2SO4 and filtrated. Evaporation of the solvent under reduced pressure followed by flash chromatography (SiO2, 95/5 hexane/EtOAc) afforded 1.0 g (98%)of Methyl 2-bromo-4-fluorobenzoate as a colourless oil.
Methyl 2-bromo-4-fluorobenzoate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Methyl 2-bromo-4-fluorobenzoate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 166)Lieferanten
653-92-9()Verwandte Suche:
- METHYL 2-BROMO-4-FLUOROBENZOATE
- Methyl 2-bromo-4-fluorobenzoate 98%
- Methyl2-bromo-4-fluorobenzoate98%
- RARECHEM AL BF 1088
- methyl 2-bromo-4-fluorobenzenecarboxylate
- Methyl 4-fluoro-2-bromobenzoate
- 5-fluoro-2-(methoxycarbonyl)bromobenzene
- Benzoic acid, 2-broMo-4-fluoro-, Methyl ester
- Bromo-4-fluorobenzoate
- 2-Bromo-4-fluorolbenzoicacid methyl ester
- 2-bromo-4-fluorobenzoate
- 2-bromo-4-fluoro-3-methylbenzoate
- 653-92-9
- blocks
- Bromides
- Carboxes
- FluoroCompounds
