Isoxsuprinhydrochlorid
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- CAS-Nr.
- 579-56-6
- Bezeichnung:
- Isoxsuprinhydrochlorid
- Englisch Name:
- ISOXSUPRINE HYDROCHLORIDE
- Synonyma:
- Navilox;isolait;Dilavase;vasoplex;Vasotran;Duvadilan;Divadilan;vasodilan;Vadosilan;suprilent
- CBNumber:
- CB5197363
- Summenformel:
- C18H24ClNO3
- Molgewicht:
- 337.84
- MOL-Datei:
- 579-56-6.mol
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Isoxsuprinhydrochlorid Eigenschaften
- Schmelzpunkt:
- 203-204°
- storage temp.
- Inert atmosphere,2-8°C
- L?slichkeit
- Sparingly soluble in water and in ethanol (96 per cent), practically insoluble in methylene chloride.
- pka
- pKa 8.0 (Uncertain);9.8 (Uncertain)
- Aggregatzustand
- Solid
- Farbe
- White to off-white
- CAS Datenbank
- 579-56-6(CAS DataBase Reference)
Isoxsuprinhydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
S-S?tze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Isoxsuprine is an adrenergic receptor modulator that has α-adrenergic receptor (α-AR) antagonist and β-AR agonist properties. It induces vasodilation of isolated equine common digital artery strips precontracted with norepinephrine, indicating an α-AR effect, and induces relaxation of isolated fowl cecum, an effect that can be blocked by the β-AR antagonist propranolol (Item Nos.
23349 |
17291). Isoxsuprine has antinociceptive effects in an acetic acid writhing test in mice. It also inhibits oxytocin-induced contractions in isolated rat uterus (IC
50 = 9.15 μM). It delays labor onset in rats by 31.63 hours when administered at a dose of 10 mg/kg per day on days 13 to 21 of gestation but increases heart rate with increasing concentration.
Chemische Eigenschaften
White Solid
Verwenden
As a vasilodator drug, Isoxsuprine Hydrochloride is used in veterinary medicine for the treatment of navicular syndrome and laminitis in horses. Isoxsuprine Hydrochloride has been shown to be a β-adrenoreceptor antagonist with β-adrenoreceptor agonistic properties, with both characteristics contributing to vasodilation and uterine relaxation. Studies suggest that Isoxsuprine Hydrochloride may be useful as a as a tocolytic agent in the treatment of preterm labour.
Isoxsuprinhydrochlorid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Isoxsuprinhydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 134)Lieferanten
579-56-6(Isoxsuprinhydrochlorid)Verwandte Suche:
- vasodilan
- vasoplex
- Isoxsuprine
- 4-Hydroxy-α-[1-[(1-Methyl-2-phenoxyethyl)aMino]ethyl]benzeneMethanol Hydrochloride
- Benzenemethanol, 4-hydroxy-.alpha.-1-(1-methyl-2-phenoxyethyl)aminoethyl-, hydrochloride
- 1-(p-Hydroxyphenyl)-2-(1'-methyl-2'-phenoxy)ethylaminopropanol-1 hydrochloride
- Benzenemethanol, 4-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-, hydrochloride (9CI)
- Benzyl alcohol, p-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-, hydrochloride (8CI)
- Dilavase
- Divadilan
- Duvadilan
- Duviculine
- Navilox
- Norephedrine, p-hydroxy-N-(1-methyl-2-phenoxyethyl)-, hydrochloride (6CI)
- Vadosilan
- Vasotran
- Aids196186
- Aids-196186
- Vasodilian
- Vasosurpine
- Isoxsuprine Hydrochloride (200 mg)
- ISOXSUPRINE HCL
- ISOXSUPRINE HYDROCHLORIDE
- 1-(p-hydroxyphenyl)-2-(1’-methyl-2’-phenoxy)ethylaminopropanol-1hydrochlorid
- 2-(3-phenoxy-2-propylamino)-1-(p-hydroxyphenyl)-1-propanolhydrochloride
- isolait
- isoxsuprinhydrochloride
- p-hydroxy-alpha-(1-((1-methyl-2-phenoxyethyl)amino)ethyl)-benzylalcohohyd
- suprilent
- p-Hydroxy-N-(1-Methyl-2-phenoxyethyl)norephedrine Hydrochlorid
- p-Hydroxy-α-[1-[(1-Methyl-2-phenoxyethyl)aMino]ethyl]benzyl Alcohol Hydrochloride
- erythro-Isoxsuprine hydrochloride
- BenzeneMethanol,4-hydroxy-a-[1-[(1-Methyl-2-phenoxyethyl)aMino]ethyl]-,hydrochloride (1:1)
- Isoxsuprine hydrochloride Solution, 100ppm
- (1RS,2SR)-1-(4-Hydroxyphenyl)-2-[(1SR)1-methyl-2-phenoxyethylamino]propan-1-ol hydrochloride
- (1RS,2SR,1′SR)-1-(p-Hydroxyphenyl)-2-(1′-methyl-2′-phenoxyethylamino)-1-propanol hydrochloride, mixture of enantiomers
- Isoxsuprine hydrochloride CRS
- 4-(1-Hydroxy-2-((1-phenoxypropan-2-yl)amino)propyl)phenol hydrochloride
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- 579-56-6
- 597-56-6
- C18H23NO3ClH
- Analytical Standards
- Analytical Chromatography Product Catalog
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