Ranolazine
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- CAS-Nr.
- 95635-55-5
- Englisch Name:
- Ranolazine
- Synonyma:
- Ranexa;Renexa;CVT 303;Renozine;RANOLAZINE;RS 43285-003;100MG/500MG/1KG;Renault oxazine;Ranolazine(Ranexa);Ranolazine (100 mg)
- CBNumber:
- CB5195172
- Summenformel:
- C24H33N3O4
- Molgewicht:
- 427.54
- MOL-Datei:
- 95635-55-5.mol
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Ranolazine Eigenschaften
- Schmelzpunkt:
- 119-1200C
- Siedepunkt:
- 624.1±55.0 °C(Predicted)
- Dichte
- 1.174±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 14.06±0.20(Predicted)
- Farbe
- White
- CAS Datenbank
- 95635-55-5(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P330 |
Mund ausspülen. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Ranolazine Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Ranolazine is an orally available, extended release drug for the treatment of
chronic angina in patients who have failed to respond to prior angina therapy.
Chronic stable angina (CSA) is a common symptom of coronary artery disease
wherein plaques in the coronary vasculature restrict blood flow to the heart,
which in turn leads to insufficient oxygenation of the heart, typically during
physical exertion or emotional stress. A vast majority of the existing anti-anginal
and anti-ischemic therapies aim to correct the imbalance between myocardial
oxygen demand and supply through mechanisms that produce reductions in
heart rate or blood pressure.
Chemische Eigenschaften
White Solid
Allgemeine Beschreibung
Ranolazine, N-(2,6-dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide (Ranexa), is an antianginal medication thatwas approved by the Food and Drug Administration (FDA)in January 2006 for the treatment of chronic angina.Ranolazine is believed to elicit its effects by altering thetranscellular late sodium current. This, in turn, alters thesodium-dependent calcium channels during myocardial ischemia.Thus, ranolazine indirectly prevents the calciumoverload that is associated with cardiac ischemia.Ranolazine is metabolized by the cytochrome CYP3A enzymesin the liver.
Ranolazine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Ranolazine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 385)Lieferanten
95635-55-5()Verwandte Suche:
- 1- 3-(2-Methoxyphenoxy)-2-hydroxypropyl -4- ...
- 1-Piperazineacetamide,N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-
- N-(2,6-dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]ethanamide
- N-(2,6-diMethylphenyl)-2-{4-[(2R)-2-hydroxy-3-(2-Methoxyphenoxy)propyl]piperazin-1-yl}acetaMide
- Ranolazine(Ranexa)
- 100MG/500MG/1KG
- Ranolazine
N-(2,6-Dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide
- Ranolazine (100 mg)
- RANOLAZINE
- n-(2,6-dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide
- 1-[3-(2-methoxyphenoxy)-2-hydroxypropyl]-4-[(2,6-dimethylphenyl)aminocarbonylmethy]piperazine
- CVT 303
- Renexa
- RS 43285-003
- (142387-99-3) ranolazine
- Ranolazine (CVT303, RS43285-003
- Ranolazine (1598744)
- Renault oxazine
- Ranexa
- Ranolazine
N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2- methoxyphenoxy)propyl]-1-piperazineacetamide
- Renozine
- Ranolazine, 10 mM in DMSO
- 95635-55-5
- 96535-55-5
- 95635-56-5
- C24H33N3O4
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Inhibitors
- RANEXA
- Pharmaceuticals
- Antianginal
- API
- APIs