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1-METHYLADENOSINE

1-METHYLADENOSINE Struktur
15763-06-1
CAS-Nr.
15763-06-1
Englisch Name:
1-METHYLADENOSINE
Synonyma:
N1-Me-rA;N1-Me-Adenosine;1-METHYLADENOSINE;Adenosine, 1-methyl-;1-methyladenosine free base;N,6-Didehydro-1,6-dihydro-1-methyladenosine;(2R,3R,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methyl-purin-9-yl)oxolane-3,4-diol;inhibit,1-Methyladenosine,1 Methyladenosine,Endogenous Metabolite,Inhibitor,1Methyladenosine;(2R,3R,4S,5R)-2-(6-Amino-1-methyl-1H-purin-9(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol;(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-imino-1-methyl-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3,4-diol
CBNumber:
CB5187128
Summenformel:
C11H15N5O4
Molgewicht:
281.27
MOL-Datei:
15763-06-1.mol

1-METHYLADENOSINE Eigenschaften

Schmelzpunkt:
>217°C (dec.)
Siedepunkt:
655.4±65.0 °C(Predicted)
Dichte
1.88±0.1 g/cm3(Predicted)
storage temp. 
−20°C
L?slichkeit
DMSO (Slightly), Water (Slightly, Sonicated)
Aggregatzustand
Solid
pka
13.24±0.70(Predicted)
Farbe
White to Off-White
PH
8.8
maximale Wellenl?nge (λmax)
258 (pH 2)；258 (pH 7)；259，260～265 (pH 13)
Stabilit?t:
Hygroscopic, Light Sensitive

Sicherheit

S-S?tze: 24/25
HS Code  29389090

1-METHYLADENOSINE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

1-Methyladenosine is a modified nucleoside generated by the processing of tRNA by methyltransferases. The urinary excretion of 1-methyladenosine is elevated in several forms of cancer, supporting its use as a biomarker in early detection. It can also be monitored in serum. Urinary levels of 1-methyladenosine also increase during active rheumatoid arthritis.

Chemische Eigenschaften

White to off-white crystalline powder

Verwenden

1-Methyl Adenosine is a modified adenosine molecule created through the processing of tRNA by methyltransferases. The presence seen to be elevated in the urinary excretion of cancer patients. Thus it may be an early diagnosis biomarker.

Definition

ChEBI: A methyladenosine carrying a methyl substituent at position 1.

1-METHYLADENOSINE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

1-METHYLADENOSINE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • N,6-Didehydro-1,6-dihydro-1-methyladenosine
  • 1-METHYLADENOSINE
  • 1-methyladenosine free base
  • (2R,3R,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methyl-purin-9-yl)oxolane-3,4-diol
  • (2R,3R,4S,5R)-2-(6-Amino-1-methyl-1H-purin-9(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
  • Adenosine, 1-methyl-
  • N1-Me-Adenosine
  • N1-Me-rA
  • inhibit,1-Methyladenosine,1 Methyladenosine,Endogenous Metabolite,Inhibitor,1Methyladenosine
  • (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-imino-1-methyl-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3,4-diol
  • 15763-06-1
  • Nucleosides, Nucleotides, Oligonucleotides
  • Nucleoside Analogs
  • Biochemicals and Reagents
  • BioChemical
  • Biochemicals and Reagents
  • Nucleoside Analogs
  • Nucleosides, Nucleotides, Oligonucleotides
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