7,8-Didehydrocholesterol Chemische Eigenschaften,Einsatz,Produktion Methoden

S-S?tze Betriebsanweisung:

S24/25:Berührung mit den Augen und der Haut vermeiden.

Chemische Eigenschaften

white to off-white fine crystalline powder. It is easy to oxidize when exposed to air.

Verwenden

7-Dehydrocholesterol is a vitamin D3 precursor, which is a sterol found in animals. Vitamin D3 is produced by the action of sunlight or ultraviolet irradiation from the precursor, 7-dehydrocholesterol (7-DC), that is synthesized in the skin of animals and humans.
In most tissues of the body, 7-dehydrocholesterol is the immediate precursor of cholesterol. It is reduced to cholesterol by the enzyme 3β-hydroxysterol-Δ7-reductase (DHCR7) in the last step of cholesterol biosynthesis. 7-DHC accumulates in Smith-Lemli-Opitz syndrome (SLOS), a disorder characterized by a mutation in the DHCR7 gene and decreased cholesterol levels in bodily tissues and fluids, as well as microcephaly, intellectual disability, and distinctive dysmorphic features. It is highly susceptible to free radical oxidation, giving rise to several oxysterols that may be involved in the pathogenesis of SLOS. 7-DHC levels are increased in brain, liver, and serum in a rat model of SLOS induced by the DHCR7 inhibitor AY 9944. 7-DHC is a provitamin that is converted to vitamin D3 by ultraviolet-B (UVB) light in a human skin equivalent system and in isolated human skin samples.

Definition

ChEBI: 7-Dehydrocholesterol is a 3β-sterol, a cholestanoid, a Delta(5),Delta(7)-sterol and a 3beta-hydroxy-Delta(5)-steroid. It has a role as a human metabolite and a mouse metabolite.

Allgemeine Beschreibung

7-Dehydrocholesterol, a 5,7-conjugated diene sterol is a biosynthetic precursor of cholesterol. It helps in the production of vitamin D3 when exposed to ultraviolet B (UVB) radiation. It has been used as an internal standard to determine sterols. 7-dehydrocholesterol is also used in the diagnosis of Smith-Lemli-Opitz syndrome. Blood and tissue of infants with Smith- Lemli-Opitz (SLO) syndrome contain reduced amounts of cholesterol and greatly increased concentrations of 7-dehydrocholesterol and of its isomer 8-dehydrocholesterol.

7,8-Didehydrocholesterol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

7,8-Didehydrocholesterol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Changsha YuTeng New Materials Co., Ltd.	+86-13487087296 +86-13787794286	rainbowz@cs-yuteng.com	China	37	58
Hebei Weibang Biotechnology Co., Ltd	+8615531157085	abby@weibangbio.com	China	8810	58
Hebei Mojin Biotechnology Co., Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12835	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5889	58
Hong Kong Excellence Biotechnology Co., Ltd.		ada@sh-teruiop.com	China	875	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	+8613343047651	admin@zlchemi.com	China	3002	58
Hebei Shengyang Water Conservancy Engineering Co., Ltd.	+8615373025980	clara@hbshengyang.com	China	875	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29880	58

434-16-2(7,8-Didehydrocholesterol)Verwandte Suche:

---

• (3)-7-Dehydrochlesterol
• (3beta)-Cholesta-5,7-dien-3-ol
• (3-beta)-cholesta-7-dien-3-ol
• (3beta)-cholesta-7-dien-3-ol
• 3-Hydroxycholesta-5,7-diene
• Cholesta-5,7-dien-3-ol, (3beta)-
• Cholesterol, 7-dehydro-
• Dehydrocholesterin
• delta(sup5,7)-cholesterol
• delta(sup7)-cholesterol
• DELTA5,7-Cholestadien-3beta-ol
• delta5,7-Cholesterol
• 5,7-Cholestandien-3.beta.-ol
• 5,7-Cholestandien-3beta-ol
• 7,8-Didehydrocholesterol
• 7-Dehydrocholesterin
• 7-dehydro-cholestero
• 7-dien-3-ol,(3.beta.)-Cholesta-5
• 7-Dehydrochlesterol
• Provitamin D₃
• 7-Dehydrocholesterol, contains ca. 1 mole of methanol of crystallization, 97.50%
• 10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
• (-)-7-Dehydrocholesterol, 3β-Hydroxy-5,7-cholestadiene, 5,7-Cholestadien-3β-ol, Provitamin D3
• 3beta-Hydroxycholesta-5,7-diene
• 7-Dehydrocholesterol, 97.5%, contains ca. 1 mole of methanol of crystallization
• 7-Dehydrocholesterol, contains ca. 1 mole of methanol of crystallization
• Δ5,7-Cholesterol
• Δ7-Cholesterol
• 7-DehydrocholesterolProvitamine
• 7-Dehydrocholseterol
• 7-Dehydrocholesterolmonohydrate,97%
• (3b)-7-Dehydrocholesterol
• 7-Dehydrocholesterol, contains ca. 1 mole of methanol of crystallization, 97.5%
• (3β)-7-Dehydro Cholesterol
• 7-Dehydrocholesterol, contains ca. 1 Mole of Methanol of crystallization, 97.5% 5GR
• IMp. B (EP): Cholesta-5,7-dien-3β-ol(7,8-Didehydrocholesterol
• 7-Dehydrocholesterol (Provitamin D3)
• DEHYDROCHOLESTEROL, 7-(AS)
• 7-Dehydrocholesterol (ProvitaMin D)
• (3-beta)-7-Dehydrocholesterol (Cholesta-5,7-dien-3-beta-ol)
• delta7-Cholesterol
• Provitamin D(sub 3)
• provitamind(sub3)
• DEHYDROCHOLESTEROL, 7-
• (-)-7-DEHYDROCHOLESTEROL
• 7-DEHYDROCHOLESTEROL
• 7-DEHYDROCHOLESTEROL MONOHYDRATE
• 5,7-CHOLESTADIEN-3-BETA-OL MONOHYDRATE
• 5,7-CHOLESTADIEN-3BETA-OL
• 3BETA-HYDROXY-5,7-CHOLESTADIENE
• PROVITAMIN D3 MONOHYDRATE
• Cholesta-5,7-dien-3-ol,(3b)-
• 7-DehydrocholesterolM (7-DHC)
• 3β-Hydroxy-5,7-cholestadiene
• 5,7-Cholestadien-3β-ol
• 17-(1,5-DIMETHYL-HEXYL)-10,13-DIMETHYL-DODECAHYDRO-CYCLOPENTA(A)PHENANTHREN-3-OL
• 7-dehydro-Cholesterol -d6
• Δ5,7-CHOLESTEROL;7-DEHYDROCHOLESTEROL