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pluviatolide

pluviatolide Struktur
28115-68-6
CAS-Nr.
28115-68-6
Englisch Name:
pluviatolide
Synonyma:
pluviatolide;trans-Pluviatolide;3α-(4-Hydroxy-3-methoxybenzyl)-4β-(1,3-benzodioxole-5-ylmethyl)-4,5-dihydrofuran-2(3H)-one;4,5-Dihydro-4β-[(1,3-benzodioxole-5-yl)methyl]-3α-(4-hydroxy-3-methoxybenzyl)furan-2(3H)-one;2(3H)-Furanone, 4-(1,3-benzodioxol-5-ylmethyl)dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4R)-;(3R,4R)-4-[(1,3-Benzodioxol-5-yl)methyl]-4,5-dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]furan-2(3H)-one
CBNumber:
CB51346359
Summenformel:
C20H20O6
Molgewicht:
356.37
MOL-Datei:
28115-68-6.mol

pluviatolide Eigenschaften

storage temp. 
Store at -20°C
L?slichkeit
DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
Aggregatzustand
A solid
LogP
2.590 (est)

Sicherheit

pluviatolide Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Pluviatolide is a lignan that has been found in B. chinense and has diverse biological activities, including antioxidant, enzyme inhibitory, and antispasmodic properties. It scavenges ABTS and 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in cell-free assays (IC50s = 23.2 and 88.5 μM, respectively). Pluviatolide inhibits matrix metalloproteinase-7 (MMP-7) with an IC50 value of 260 μM. It decreases contractions induced by acetylcholine in isolated guinea pig ileum when used at concentrations of 30 and 100 μM.

Definition

ChEBI: A butan-4-olide that is dihydrofuran-2(3H)-one which is substituted by a vanillyl group at position 3 and by a 3,4-methylenedioxybenzyl group at position 4 (the R,R stereoisomer).

pluviatolide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


pluviatolide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 20)Lieferanten
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Shanghai Jizhi Biochemical Technology Co. Ltd. 4009004166/18616739031 18616739031
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  • pluviatolide
  • (3R,4R)-4-[(1,3-Benzodioxol-5-yl)methyl]-4,5-dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]furan-2(3H)-one
  • 3α-(4-Hydroxy-3-methoxybenzyl)-4β-(1,3-benzodioxole-5-ylmethyl)-4,5-dihydrofuran-2(3H)-one
  • 4,5-Dihydro-4β-[(1,3-benzodioxole-5-yl)methyl]-3α-(4-hydroxy-3-methoxybenzyl)furan-2(3H)-one
  • trans-Pluviatolide
  • 2(3H)-Furanone, 4-(1,3-benzodioxol-5-ylmethyl)dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4R)-
  • 28115-68-6
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