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6-hydroxydexamethasone

6-hydroxydexamethasone Struktur
55879-47-5
CAS-Nr.
55879-47-5
Englisch Name:
6-hydroxydexamethasone
Synonyma:
6-hydroxydexamethasone;6β-hydroxy Dexamethasone;Dexamethasone Impurity 12;Dexamethasone 6β-Hydroxy Impurity;Dexamethasone 6beta-Hydroxy Impurity;6-Hydroxydexamethasone Solution, 100ppm;(6R,8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-6,11,17-trihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
CBNumber:
CB51341435
Summenformel:
C22H29FO6
Molgewicht:
408.46
MOL-Datei:
55879-47-5.mol

6-hydroxydexamethasone Eigenschaften

Schmelzpunkt:
259-262°C
Siedepunkt:
613.2±55.0 °C(Predicted)
Dichte
1.38±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
L?slichkeit
Dioxane (Very Slightly, Sonicated), Methanol (Slightly)
Aggregatzustand
Solid
pka
12.06±0.70(Predicted)
Farbe
White to Light Yellow

Sicherheit

6-hydroxydexamethasone Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

6β-hydroxy Dexamethasone is a metabolite of dexamethasone (Item Nos. 11015 | 20340) that is more hydrophilic than the parent compound. Dexamethasone is metabolized by CYP3A4; therefore, quantification of the dexamethasone metabolites, 6α- and 6β-hydroxy dexamethasone, can be used to determine CYP3A4 enzyme activity in humans. The formation of 6-hydroxy dexamethasone metabolites is species-specific, with hamsters producing the highest amount. In rats, dexamethasone hydroxylation is sex-specific, with male rats producing metabolites in similar ratios to humans and female rats producing fewer hydroxylated metabolites than male rats.

Chemische Eigenschaften

Off-White Solid

Verwenden

The hydrophilic metabolite of Dexamethasone (D298800).

6-hydroxydexamethasone Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

6-hydroxydexamethasone Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 31)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Standardpharm Co. Ltd. 		86-714-3992388
overseasales1@yongstandards.com United States 14332 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
China National Standard Pharmaceutical Corporation Limited 		+8615391658522
 overseasales@yongstandards.com China 11922 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
 jkinfo@jkchemical.com China 96815 76
Chemsky（shanghai）International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32321 50
S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-83725681-603
China 4496 50
Clearsynth Labs Limited +91-22-26355700
info@clearsynth.com India 9679 58
Alta Scientific Co., Ltd. 022-6537-8550 15522853686
 sales@altasci.com.cn China 4511 55
BOC Sciences 16314854226
 info@bocsci.com United States 9923 65
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684;
 sales@rrkchem.com China 57423 58

55879-47-5()Verwandte Suche:

  • 6-hydroxydexamethasone
  • Dexamethasone 6β-Hydroxy Impurity
  • Dexamethasone Impurity 12
  • 6-Hydroxydexamethasone Solution, 100ppm
  • (6R,8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-6,11,17-trihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
  • Dexamethasone 6beta-Hydroxy Impurity
  • 6β-hydroxy Dexamethasone
  • 55879-47-5
  • C22H29FO6
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Steroids
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