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1,3-dipropyl-8-(3-noradamantyl)xanthine

1,3-dipropyl-8-(3-noradamantyl)xanthine Struktur
136199-02-5
CAS-Nr.
136199-02-5
Englisch Name:
1,3-dipropyl-8-(3-noradamantyl)xanthine
Synonyma:
MK-7418;KW-3902;HMR-4902;Rolofylline;KW-3902 >=98% (HPLC);KW-3902|||MK-7418|||KF-15372;1,3-dipropyl-8-(3-noradamantyl)xanthine;8-(Hexahydro-2,5-methano-pentalen-3a-yl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione;8-(Hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,7-dihydro-1,3-dipropyl-1H-purine-2,6-dione;1H-Purine-2,6-dione, 8-(hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,9-dihydro-1,3-dipropyl-
CBNumber:
CB51337919
Summenformel:
C20H28N4O2
Molgewicht:
356.46
MOL-Datei:
136199-02-5.mol

1,3-dipropyl-8-(3-noradamantyl)xanthine Eigenschaften

Siedepunkt:
578.0±42.0 °C(Predicted)
Dichte
1.262±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
L?slichkeit
DMSO: soluble20mg/mL
Aggregatzustand
solid
pka
9.23±0.70(Predicted)
Farbe
White to off-white
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
WGK Germany  3
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H413 Kann für Wasserorganismen sch?dlich sein, mit langfristiger Wirkung. Langfristig (chronisch) gew?ssergef?hrdend Kategorie 4
Sicherheit

1,3-dipropyl-8-(3-noradamantyl)xanthine Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

KW 3902 is an antagonist of the adenosine A1 receptor (Ki = 0.19 nM). It displays 890-fold selectivity for A1 receptors over A2A receptors and has no activity at A3 receptors. KW 3902 less potently inhibits human organic anion transporter 1 (OAT1; Ki = 7.82 μM). KW 3902 exhibits renal protective effects during hypoxemia in rabbits.

Verwenden

KW 3902 is an adenosine A1-receptor antagonist, which has recently been shown to alleviate axonopathy caused by human Tau ΔK280. KW 3902 can be considered for the development of a treatment towards hypometabolism and neuronal dysfunction associated with Tau-induced neurodegenerative diseases.

1,3-dipropyl-8-(3-noradamantyl)xanthine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

1,3-dipropyl-8-(3-noradamantyl)xanthine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 41)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695
 laboratory@coreychem.com China 30238 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
 sales@hzclap.com CHINA 6312 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9806 58
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686
 sales@rechemscience.com China 2992 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11218 58
Guangzhou Younan Technology Co., Ltd 020-82000279 18988968278
 sales@ubiochem.com China 4297 58
  • 1,3-dipropyl-8-(3-noradamantyl)xanthine
  • HMR-4902
  • KW-3902
  • Rolofylline
  • 8-(Hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,7-dihydro-1,3-dipropyl-1H-purine-2,6-dione
  • MK-7418
  • 8-(Hexahydro-2,5-methano-pentalen-3a-yl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione
  • 1H-Purine-2,6-dione, 8-(hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,9-dihydro-1,3-dipropyl-
  • KW-3902 >=98% (HPLC)
  • KW-3902|||MK-7418|||KF-15372
  • 136199-02-5
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